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Biomedical subjects

E Capodaglio

Publications and source records attributed to E Capodaglio.

At least 37 records · Page 2Linked to original sources
PubMed1985

Urine/air partition coefficients for some industrially important substances.

The urine/air and blood/urine partition coefficients (lambda) of 43 commonly employed organic solvents (Aliphatic, Cyclic, Aromatic and Halogenated Hydrocarbons, Ketones, Alcohols and Esters) are reported. The analyses were performed by the multiple equilibration method (constant pressure method) using a Hewlett-Packard 5880 gas chromatograph. The lambda values proposed can be employed in the field of biological monitoring of subjects occupationally exposed to solvents vapors.

Air Pollutants, Occupational↗
PubMed1984

[N-hexane and toluene in the urine of occupationally exposed subjects. Measurement and significance of its presence].

N-hexane and toluene in the urine of occupationally exposed subjects. Measurement and significance of their presence. The determination of n-hexane and toluene in urine was performed in 23 subjects who were occupationally exposed to n-hexane and in 8 subjects exposed to toluene, by means of the head space technique. A Hewlett-Packard 5880 A gas chromatograph supplied with Hewlett-Packard 5970 A Mass Selective Detector was employed. The Authors found significant correlations between urine concentration of the substance and environmental concentration (for n-hexane r = 0,866; for toluene r = 0,770.

Adult↗
PubMed1984

n-Hexane urine elimination and weighted exposure concentration.

The concentration of n-hexane in urine was determined in 30 subjects occupationally exposed to n-hexane (median value 59.6 mg/m3) in a shoe factory. The measurement of the substance was performed by means of a Hewlett-Packard 5880 gas chromatograph supplied with a Hewlett-Packard 5970 Mass Selective Detector. The analyses were performed by the head space method (constant volume method, after determination of the urine partition coefficient by the multiple phase equilibration method). The authors found a significant correlation between the n-hexane urine concentrations (microgram/l, Cu) and the n-hexane environmental concentrations (mg/m3, Ci) (r = 0.84; Cu = 0.0669 X Ci + 0.8396).

Adult↗
PubMed1983

[Measurement of the coefficient of solubility of airborne substances in blood. II. Solvents of wide industrial use].

A list of industrial solvents largely employed and produced in Italy (and somewhere else too) is presented. Using two methods previously described, blood/air partition coefficient of such solvents have been measured. Then a discussion is made about the possibility of their employment in the field of biological monitoring of subjects professionally exposed to solvent vapours.

Acetates↗
PubMed1983

[Use of passive personal samplers in industrial hygiene].

Passive personal samplers are very easy devices to monitor occupational exposure and today they are wildely used on the field. In this study we don't speak about background theory of passive sampler but we critically review parameters influencing the results like: maximum and minimum detectable concentration, adsorbing substrate, sampling time, answer time, control and comparison with standard methods. We also illustrate some industrial hygiene strategy to use passive personal sampler on the field, the possible goals, the individuals of which we need collaboration.

Air Pollutants, Occupational↗
PubMed1982

[Evaluation of a new alveolar air sampler].

A new alveolar air sampler is described and tested; it can be used in monitoring subjects exposed to gas and vapours in their working places. The tests were made under different experimental conditions, using both vapours of industrial solvents as acetone, ethanol, trichloroethylene, methyl ethyl ketone, n-hexane, ethyl acetate and respiratory gas (O2, CO2).

Acetone↗
PubMed1976

[Functional conditions of the respiratory system and work site pollution. III. Relationships between "risk indicators" and "respiratory risk" in a chemical industry (author's transl)].

The results are reported of a retrospective study carried out by the authors on 717 workers of a chemical industry whose exposure was diversified and quantified through a work environment survey. A comparison between "risk indicators" and both objective (respiratory function changes) and subjective (chronic bronchopneumopathy symptoms) "risks" showed a significant probability of the causal role played by work environment pollution in respect of the repiratory changes found by the authors.

Air Pollutants↗
PubMed1975

[Functional conditions of the respiratory system and work site pollution. II. Prevalence of respiratory function changes in workers employed in bichromate and chromic acid production (author's transl)].

The authors report the prevalence of respiratory function changes in two groups of workers employed in bichromate and chromic acid production. In the first group (82 subjects) examined at the Institute of Occupational Medicine, the following tests were performed: filling out of a questionnaire for cronic bronchitis; chest x-ray; spirometry; pulmonary diffusing capacity (DLco) measurement; blood gas analysis on arteriolized capillary; He and CO2 rapid expiratory curves determination. No environmental pollution data were available. In the second group (180 subjects) examined at the working site, the following tests were performed: filling out of a questionnaire -or chronic bronchitis; spirometric determination. Environmental pollution data were available. A causal connection is hypothesized by the authors between either roentgenologic or respiratory functional changes and chromium exposure, and an increased proportion between lung function changes and exposure length is stressed.

Adult↗
PubMed1975

[Measurement of "flow-volume" curves and "closing volume" in occupational medicine. Normal findings in healthy subjects (author's transl)].

A method is described for measuring, by a single test, some functional respiratory indexes, such as lung volumes, dynamic tests (flow-volume curve included), rapid He and CO2 curves, "closing volume". The normal values of "closing volume" and of forced expiratory flows obtained in 114 healthy subjects (65 men and 49 women) are then reported. Such values are comparable to those obtained by other authors. An equipment is used by the authors which is easily transportable to the workplace; their method can therefore be used for surveys of workers exposed to occupational respiratory risk during a working shift. The described respiratory index should be able to detect in a pre-clinical stage the early functional changes in chronic bronchitis.

Adult↗
PubMedDate not supplied

Urinary excretion of tetrachloroethylene (perchloroethylene) in experimental and occupational exposure.

Fifteen human volunteers were exposed to tetrachloroethylene (perchloroethylene, tetrachloroethene) vapor at 3.6-316 mg/m3 for 2-4 hr at rest (10 cases) and during light physical exercise (5 cases). Subsequently, 55 workers who were occupationally exposed to tetrachloroethylene in eight commercial dry cleaning facilities were studied (median value, 66 mg/m3; geometric standard deviation, 3.15 mg/m3). In both the experimentally exposed subjects and occupationally exposed workers the urinary concentration of tetrachloroethylene showed a linear relationship to the corresponding environmental time-weighted average concentration. The findings indicate that the urinary concentration of tetrachloroethylene can be used as an appropriate biological exposure indicator. In occupationally exposed subjects performing moderate work, the urinary tetrachloroethylene concentration corresponding to the time-weighted average of the threshold limit value proved to be 120 mcg/L and its 95% lower confidence limit (biological threshold) 100 mcg/L. The effects of workload on the tetrachloroethylene urinary elimination are also accounted for.

Adult↗