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E Carletti

Publications and source records attributed to E Carletti.

5 recordsLinked to original sources
PubMed1999

Functional analysis of the evolutionarily conserved proline 53 residue in Proteus mirabilis glutathione transferase B1-1.

The role of the evolutionarily conserved residue Pro-53 in Proteus mirabilis glutathione transferase B1-1 has been examined by replacing it with a serine residue using site-directed mutagenesis. The effect of the replacement on the activity, thermal stability and antibiotic binding capacity of the enzyme was examined. The results presented support the view that Pro-53 participates in the maintenance of the proper conformation of the enzyme fold rather than playing a direct role in the catalytic reaction. Furthermore, this residue appears to be an important determinant of the antibiotic binding to the enzyme. Experiments with wild type and mutated enzymes provide evidence that glutathione transferases may play an important role in antibiotic resistance exhibited by bacteria.

Amino Acid Sequence↗
PubMed1985

Indirect radiographic and angiographic signs of isolated left superior vena cava in congenital heart disease.

Blood that drains into the right atrium through an isolated left superior vena cava (LSVC) can be a complicating condition during cardiac surgery. In cases of LSVC, a double shadow can be present on standard chest X-ray over the left mediastinum. A notch along the lower contour of left atrium has been previously reported by Owen et al. in 4 cases as an indirect sign of this LSVC anomaly. These two indirect signs were evaluated in 135 (4.5%) cases of LSVC, viewing 89 chest radiographs and 40 angiograms. Their incidence, separately (17-45%) or in combination (9-20%), was observed to be frequent enough to justify a systematic search of these signs in open-heart surgery candidates.

Angiography↗
PubMed1984

Interruption of the aortic arch in an infant with left subclavian steal syndrome. Case report.

An unusual case of interruption of the aortic arch with flow to the descending aorta through the left vertebral and left subclavian arteries is described. The ductus arteriosus was functionally closed. The aortic arch was reconstructed with a PTFE graft, but the patient died because of lung problems, related to a high left-to-right shunt through a ventricular septal defect. A new surgical approach is postulated in view of the unusual hemodynamic features. Surgical control of pulmonary congestion could be the initial step, followed by aortic arch reconstruction later when insertion of a non-restrictive aortic prosthesis is possible.

Aorta, Thoracic↗
PubMedDate not supplied

[Nursing documentation in the Stroke Unit].

The organization of Stroke Unit improved prognosis of stroke patient. The randomized studies emphasized the importance of nursing in such a structure. In order to improve nursing process in our Stroke Unit, we designed a nurse record which includes a neurological scale, to define dependence classes and guidelines based on Virgina Henderson's theoretical model. In this paper, we present this nurse record and we describe the various steps of its design.

Hospital Units↗