[Continuous infusion of propofol versus thiopentone-isoflurane: comparative study of the protection against surgical stress in children].
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Biomedical subjects
Publications and source records attributed to E Carrillo.
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We report 2 patients who developed massive pulmonary embolism with greater than 50% occlusion of the pulmonary arterial circulation. Hypotension, syncope and right sided failure were the clinical manifestations. Immediately after diagnostic pulmonary arteriography, 20,000 U of streptokinase (SK) were delivered in the pulmonary artery next to the thrombotic mass. A continuous infusion of SK, 10,000 U/h was maintained for 24 h in one patient and 72 h in the other. Rapid clinical improvement was observed in the following 24 h. Control angiography showed lysis of the embolus with residual obstructions of segmentary branches. The clinical value of this form of treatment for pulmonary embolism is discussed.
1. We studied the effects of a calcium antagonist diltiazem, as well as diazepam and phenytoin on hyperthermia induced seizures in unrestrained 15 day-old rats. 2. Saline injected animals exposed to an ambient temperature of 40 degrees C showed a gradual increase in body temperature reaching a maximum of 42 +/- 0.1 degree C at 50 min. 3. At this time all rats pups had generalized seizures. 4. Similar results were obtained when the animals were pretreated with phenytoin (100% showed seizures). 5. Animals receiving diltiazem had a temperature of 41.5 +/- 0.1 degree C at 90 min of exposure to 40 degrees C environment. 6. However, diltiazem completely prevented seizures. 7. The rats treated with diazepam showed lower temperature than in saline, diltiazem and phenytoin groups and no seizures were observed in this experimental group.
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Ataques de nervios ("attacks of nerves") have been discussed in the psychiatric and anthropological literature for over thirty years. The early psychiatric articles focused on the pathology expressed by the ataque. More recent articles by anthropologists and Latino mental health professionals have reconceptualized the ataque through understanding its cultural meaning and the social factors which provoke an ataque de nervios. This article is a contribution to this reinterpretation of the ataque de nervios among Latinos. Through a series of case studies, we argue that the ataque is an expression of anger and grief resulting from the disruption of family systems, the process of migration, and concerns about family members in peoples' countries of origin.
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At input multiplicities between 5-10 UFP/cell FMDV O1 Caseros adsorb in BHK21 Clon 13 cells at a rate of 5-20% depending whether cells are in suspension or in monolayers. At least four washings with medium are required to eliminate non specifically adsorbed virions. The remaining attached virus appears to be in contact with "specific" receptors of the cytoplasmic membrane. After penetration, 80% of virus became degraded to slow molecular weight material which is detected at first in the subcellular fraction and is gradually excreted out of the cells. The degradation process occurs from 0 to 15 minutes and it is demonstrated by a parallel decrease in infectivity and stability of purified labelled FMDV O1 Caseros. The 20% remaining virus is found firmly attached to a subcellular fraction precipitable at 15,000 xg. Parental residual infectivity remains remarkably stable for 90 min at which time newly synthetized RNA appears. Fraction of 15,000 xg from infected cultures was obtained at 60 min PI and incubated in vitro at 37 C. The infectivity remains unaltered for a period of 120 min even if the preparation is treated with 0.2% of triton x 100. Fraction of 15,000 xg from infected and control cultures obtained at different time PI were seeded on a linear sucrose gradient. A sharp peak of acid phosphatase associated with the lower mobility bands indicates the presence of intact lysosome structures. A shoulder of the enzyme activity is detected between the two main protein bands. Associated with the region rich in unbroken lysosomes, a very sharp peak of infectivity and/or 3H uridine or 32P labelled incoming virus can be detected. A different pattern of the residual incoming infectivity is found associated with the more rapid sedimentation protein band. 3H uridine incorporation at the beginning of viral RNA synthesis initiation shows that an important amount of newly synthesized viral RNA is found in the lower mobility band of the 15,000 xg fraction. Some incorporation is also detected in the faster band. The results presented here suggest that some functional activity is associated with the residual virus present at the beginning of infection in the 15,000 xg fraction. It can also be accepted that this virus penetrates by pinocytosis of specific receptors at the cytoplasmic membrane.
One of the most important principles of surgical correction of urinary stress incontinence is the restoration of the urethrovesical angle to its original anatomic position. A new variant of urethropexy, suspending the vaginal wall from the anterior rectus fascia, is presented. To accomplish this goal, a special ligature carrier needle was designed. The ligatures are carried with this needle from the vaginal wall, through the space of Retzius, and upward above the rectus fascia where they are tied across the midline, one side to the other. This report describes the new method in detail. Using this technique, urethropexy was performed on 98 patients at the UCLA Olive View Medical Center. The overall cure rate for urinary stress incontinence was over 95% at 6-months to 3-year follow-up. The most common complications were postoperative urinary retention and urinary tract infection. The average length of hospitalization was 5 days.
The fallopian tube's remarkable mobility and inherent length makes possible its exteriorization from the abdominal cavity to perform any kind of tubal sterilization. We offer a new laparoscopic technique utilizing (1) exteriorization of the tube and the performance of either (a) tubal ligation (Pomeroy technique); or (b) unipolar cauterization, or (2) intraabdominal in-sleeve cauterization in case of failure to exteriorize the tube. Our approach, on the one hand, was to avoid laparotomy but still preserve the advantages of tubal ligation, and on the other hand, to avoid possible bowel burn but still retain the beneficiary effect of electrical cauterization. To accomplish this, a simple second puncture uninsulated trocar-sleeve and grasping forceps were designed. With this technique, 325 patients have had voluntary interval sterilization at Olive View Medical Center-UCLA Campus (1977-1980). No bowel burn or pregnancies have occurred. No laparotomies have been necessary. Complications were minor and compared favorably with those cases in which other techniques were used.
The normal mobility and inherent length of the fallopian tube make possible its exteriorization from the abdominal cavity to perform tubal sterilization. The authors offer a new laparoscopic technique using exteriorization of the tube, performance of either tubal ligation (modified Pomeroy technique) or unipolar cauterization, and intra-abdominal in-sleeve cauterization in case of failure to exteriorize the tube. This approach averts laparotomy, preserves the advantages of tubal ligation, and precludes bowel injury that may result from using electric cauterization. To ensure safety an uninsulated trocar sleeve and grasping forceps were designed and used through the second puncture site. With this technique, 364 patients have had voluntary interval sterilization at the UCLA-Olive View Medical Center between 1977 and 1980, including tubal ligation (181 patients), cauterization (161), and intra-abdominal in-sleeve cauterization (22). No bowel burn was occurred and no laparotomies have been necessary. Complications were minor and compared favorably with other laparoscopic sterilization techniques.
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