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Biomedical subjects

E Ceccolini

Publications and source records attributed to E Ceccolini.

5 recordsLinked to original sources
PubMed1991

Extramedullary cutaneous plasmacytoma.

Neoplastic degeneration of plasma cells can show different clinical features, including multiple myeloma and plasma cell leukemia. Skin involvement is not rare in patients with multiple myeloma, and represents a poor prognosis. Appearance of a cutaneous plasmacytoma without the involvement of bone marrow is very rare. We describe a patient who had cutaneous plasmacytoma, with two solitary lesions of the oral cavity. The patient also showed a cerebral involvement, but no evidence of multiple myeloma, with normal-appearing bone marrow.

Humans↗
PubMed1988

A long-term study on the use of evening primrose oil (Efamol) in atopic children.

The effect of essential fatty acids on atopic eczema is controversial. Some workers have reported that patients with atopic eczema improved following oral treatment with evening primrose oil (an oil with a high concentration of gamma-linolenic acid), but others have disputed this. This study was designed to look at the effect of evening primrose oil as a long-term oral supplementation for children with atopic eczema. Treated children dramatically improved their clinical condition after 4 weeks of therapy, and this improvement was maintained during the whole period of treatment (20 weeks). At the same time, modifications in plasma, neutrophil and lymphocyte fatty acid composition were detected.

Child, Preschool↗
PubMed1988

Evening primrose oil (Efamol) in the treatment of children with atopic eczema.

It has been reported that essential fatty acid levels may be low and that there may be reduced levels of delta-6-desaturase metabolites of linoleic acid in patients with atopic eczema. Good therapeutic results have been reported on the use of evening primrose oil (Efamol) in adults but not in children. Efamol contains gamma-linolenic acid, the delta-6-desaturase metabolite of linoleic acid. The authors have studied 24 children with atopic eczema: 12 of them were treated with a higher dose of evening primrose oil than in previous studies and 12 with placebo olive oil. The clinical status and plasma, neutrophil and lymphocyte fatty acid composition in these children have been evaluated. After 4 weeks the eczema of essential fatty acid-treated children significantly improved in comparison with that of placebo-treated children (p less than 0.01). There were significant changes in plasma fatty acid composition between the basal values and the end of active treatment, and between the placebo and actively treated children. Neutrophil and lymphocyte fatty acid composition did not seem to be related to disease activity.

Child, Preschool↗