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Biomedical subjects

E Chavez

Publications and source records attributed to E Chavez.

27 records · Page 2Linked to original sources

Potassium deficiency in the adult male chicken.

Adult male chickens, which were maintained on a low dietary potassium intake for 11 weeks showed no gross abnormalities, but had significantly reduced feed intake and losses of body weight. Adult male chickens had a physiological capacity to increase the biological half life of their body potassium from 18 to 134 days when the dietary potassium was reduced from .32 to .02%. However, the deficient birds were unable to balance their intake with the excretion because of the obligatory loss of potassium. The relative specific activity of different tissues in adult male chickens determined at different time intervals after the intravenous injection of potassium-42 indicated that the plasma pool potassium had the highest turnover rate of potassium in the body. In decreasing order, it was followed by the skin, heart, liver, intestine, bone, and muscle. The daily balance of potassium in adult male chickens maintained under optimum and sub-optimum dietary potassium intake gave an estimated minimum requirement for this element of .06% of the diet.

Animals↗

Methionine toxicity in chicks and poults.

In feeding experiments with poults, 2% DL-methionine caused a marked growth depression which could be alleviated by the addition of glycine. Homocystine at an equimolar level depressed growth to a lesser degree than methionine, and this growth depression could be alleviated by glycine. Betaine could alleviate the growth depression of homocystine but not that of methionine. Methionine-fed poults developed a cervical paralysis similar to that of a folic acid deficiency, but the addition of this vitamin at several times the requirement was ineffective in counteracting the toxicity of methionine in either chicks or poults.

Animals↗

Registry of experimental cancers of the National Cancer Institute.

This report describes the organization and functions of the Registry of Experimental Cancers and gives the chronology of events that led to its establishment. Currently 21,500 accessions have been coded; the vast majority are spontaneous and induced cancers, chiefly of rodents, and also a wide variety of nonneoplastic diseases. Accessions are accepted from contributors working in laboratories in this country and abroad. The material is available for study by responsible scientists, and a limited number of study sets is available for loan on request.

Animals↗