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E Cornu

Publications and source records attributed to E Cornu.

44 records · Page 3Linked to original sources
PubMed1992

[Necrotizing fasciitis: a medical and surgical emergency. Apropos of a case].

We report about a 66-years-old obese and diabetic female patient, treated with anti-inflammatories for osteoarthritis of the hip and operated for varices of the lower limbs by a bilateral stripping of the internal saphenous veins, who presented with a mortal necrotizing fasciitis during the postoperative period. Necrotizing fasciitis is a severe, infrequent disease jeopardizing the vital prognosis, in which an appropriate and early treatment (medical, using antibiotics, and surgical by extensive debridement) can prevent a fatal outcome. The most often involved germs are streptococci (45%). The association of anaerobic and aerobic germs sometimes causes mixed cellulitis. The vital prognosis is always threatened by postoperative fasciitis. The mortality rate ranges from 50 to 75%, the main causes of death being a septic shock or pulmonary embolism. The functional prognosis of the surviving patients depends on the extent and quality of surgery.

Aged↗
PubMed1988

[Vascular anastomoses of small caliber vessels. Comparison between continuous or interrupted sutures].

Continuous sutures are generally used to perform anastomoses on vessels less than 2 mm in diameter, but some surgeons advocate interrupted sutures which they claim cause less stenosis and provide better vascular potency in the long term. Arteriovenous fistula for chronic haemodialysis is a good model of anastomosis on 1 to 2 mm wide vessels. We used this model to compare the 2 techniques in 2 randomized groups of 20 patients each. The type of suture (continuous or interrupted) was drawn by lot in non diabetic patients who were having their first fistula for chronic haemodialysis. All anastomoses were performed by end-to-side implantation of a superficial vein onto the radial artery. Prolene 8/0 was used as suture material. The maximum follow-up period was 2 years. No significant difference in vascular potency could be demonstrated between the 3 groups. Thus, continuous sutures performed under suitable conditions can be used to perform with greater ease anastomoses which are as patent as those performed with interrupted sutures.

Arteriovenous Shunt, Surgical↗
PubMedDate not supplied

[Acute dissection of the infrarenal aorta and horseshoe kidney. Apropos of a case and review of the literature].

We report about one case of acute dissection of the infrarenal abdominal aorta associated with a horseshoe kidney. A few points in the history of this 47-year-old patient deserve being underscored: the absence of an "etiological" factor of aortic dissection, the presence of five renal arteries, illustrating the complex vascularity of a horseshoe kidney, the specific surgical problems arising from both a lesion of the aortic junction and a horseshoe kidney. On the basis of the literature, we underline the incidence of dissection of the infrarenal aorta (1 to 3%), that of horseshoe kidney (0.15%) and that of pathology of the aortic junction in patients with a horseshoe kidney, which seems to be accidental.

Aortic Dissection↗
PubMedDate not supplied

[Surgical treatment of pulmonary metastases].

Between 1977 and 1986, 23 patients with pulmonary metastases were operated upon in a thoracic and cardiovascular surgery department, totalling 26 thoracotomies. The time elapsed between treatment of the primary tumour and that of the metastasis (single or multiple) ranged from 11 to 89 months. The metastases were discovered on follow-up x-ray films of the chest in 15 cases. All patients underwent preoperative lung function assessment, pulmonary radiotomography or thoracic computerized tomography and bronchial fibroscopy. Surgery consisted of tumorectomy (12 cases), lobectomy (5 cases), pneumonectomy (3 cases), segmentectomy (1 case) and tumorectomy combined with lobectomy (1 case). In 2 patients only exploratory thoracotomy could be performed. The operative mortality was nil. The mean survival counted from the date of the last thoracotomy was 17 months (range 1 to 51 months). The mean absolute survival was 24 months (range 13 to 51 months). The actuarial survival rate was 60 percent at 1 year, 47 percent at 2 years and 26 percent at 3 years. Terminal respiratory failure was the main cause of death. Surgery within a multidisclinary approach of lung cancer must therefore spare as much lunch parenchyma as possible to preserve the patient's future.

Adult↗
PubMedDate not supplied

Platelet-activating factor and haematopoiesis. XI. Platelet-activating factor has no effect on the production of interleukin-6 and tumor necrosis factor-alpha by human bone marrow stromal cells.

PAF is a phospholipid mediator of inflammation with stimulates IL-6 production by murine skin fibroblasts. Although PAF is present in human bone marrow, its role in haematopoiesis is unknown. We have assessed whether PAF stimulates IL-6 and TNF-alpha production by human bone marrow stromal cells (mostly fibroblast-like cells). We report that PAF (1 nM to 10 microM) has no effect on the synthesis of IL-6 and TNF-alpha by human bone marrow stromal cells. This difference may be due to the widely accepted concept "tissue-specific fibroblasts". The role of PAF in the regulation of human haematopoiesis remains to be elucidated.

Bone Marrow↗