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Biomedical subjects

E Czecior

Publications and source records attributed to E Czecior.

At least 19 recordsLinked to original sources
PubMed2005

Sleep study in patients with overweight and obesity.

Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by repetitive collapse of the pharyngeal airway during sleep, which leads to oxygen desaturation, sleep fragmentation and daytime somnolence. Obesity is one of the most important risk factor for the development of OSAS. The exact mechanisms responsible for the relationship between obesity and OSAS are still unclear. The fat deposits in the pharynx region as well as the reduction in the lung volume have been considered as factors that might be responsible for the increase of the upper airway collapsibility. The aim of our study was to evaluate the correlation between the Body Mass Index (BMI) and sleep study parameters in overweight and obese patients suffering from breathing disturbances during sleep. We studied a group of 106 consecutive obese or overweight patients with a primary complaint of snoring or other breathing disturbances during sleep. In all cases, BMI and sleep studies (PolyMESAM) were examined. We evaluated relationship between the BMI and sleep study parameters such as Respiratory Disturbance Index (RDI), Apnea Index (AI), Desaturation Index (DI) and Average of Lowest Saturation (LSAT). The results showed the lack of significant statistical correlations between BMI and all the sleep parameters studied in the overweight patients and the statistical positive correlation between the BMI and RDI in the obese cases. We conclude that BMI determination may be considered as a simple, yet important predictor, of the OSAS in the group of obese patients.

Adult↗
PubMed2002

Comparison of the efficacy and tolerability of amoxycillin/clavulanic acid 875 mg b.i.d. with cefuroxime 500 mg b.i.d. in the treatment of chronic and acute exacerbation of chronic sinusitis in adults.

The efficacy and safety of amoxycillin/clavulanic acid (AMX/CA) (875/125 mg b.i.d. for 14 days) were compared with that of cefuroxime axetil (500 mg b.i.d. for 14 days) in a multicenter, open, parallel-group, randomized clinical trial in 206 adults with chronic or acute exacerbation of chronic sinusitis. Clinical response was similar, with 95% of AMX/CA-, and 88% of cefuroxime-treated, clinically evaluable patients cured (95% confidence interval; -0.6% to +15%). In bacteriologically evaluable patients, cure rates, defined as eradication of the original pathogen with or without re-colonization with non-pathogenic flora, were also similar, with 65% of AMX/CA- and 68% of cefuroxime-treated patients cured (95% confidence interval; -18% to +15%). However, clinical relapse was significantly higher in the cefuroxime group: 7% (7/89) of clinically evaluable patients, compared with 0% (0/98) in the AMX/CA (p=0.0049) group. A similar incidence of possible or definite adverse events related to the study drug was reported for both treatments (AMX/CA 4.4%, cefuroxime 4.3%), the most frequent being diarrhea. Four adverse events were recorded as serious or life-threatening with only one considered related to the study drug (urticaria, cefuroxime). AMX/CA 875/125 mg b.i.d. for 14 days is as effective and well tolerated as cefuroxime axetil 500 mg b.i.d. for 14 days in the treatment of chronic, or acute exacerbation of chronic sinusitis, but is associated with a significantly lower clinical relapse rate.

Administration, Oral↗
PubMed2001

Recurrent laryngeal nerve palsy after thyroid cancer surgery: a laryngological and surgical problem.

Recurrent laryngeal nerve paralysis is one of the most frequent complications after thyroid surgery due to goiter and cancers. A higher probability of this complication occurs after secondary procedure of the thyroid and in malignant cases. The symptoms may differ and depend on many factors. Generally, patients need careful ENT and surgical care including diagnosis and treatment. Four hundred and sixty-six patients who underwent thyroid operation due to cancer were analyzed. The group was composed of 227 papillary carcinoma, 87 follicular carcinoma, 51 medullary carcinoma, and 101 anaplastic carcinoma. Two hundred and fifty-three total thyroidectomies, 82 lobectomies and subtotal second lobe operations, 91 subtotal thyroidectomies, and 40 biopsies (wedge resections) were performed. In all 426 total and subtotal thyroidectomies an attempt to identify the recurrent laryngeal nerves was carried out. For 360 patients (77%) the surgical procedure was primary and for 106 patients (23%) the operation was secondary. Preoperative and postoperative laryngoscopic examinations were performed in all patients. Every patient with palsy underwent special laryngological procedures if needed (tracheotomy, phoniatric rehabilitation, conservative treatment and surgery in lack of improvement). The rate of postoperative vocal cord paralysis was 4.7%. The permanent palsy rate was 3.5%. In 1.2% recovery was observed. Of the 4.7% palsy rate, 3.2% concerned unilateral palsy and 1.5% bilateral pathology. Using the chi2 test, no significant differences between the rate of unilateral and bilateral paralysis and between temporary and permanent paralysis were found. On the basis of our material and results, identification the recurrent laryngeal nerves should be mandatory at surgery, thereby avoiding paralysis. Special laryngological procedures and surgical care from the beginning of paralysis are necessary for patients with vocal cord palsy. It allows to diagnose and treat patients with quite good results.

Humans↗
PubMed2000

[An influence of combined treatment of laryngeal cancer on thyroid gland activity].

The aim of the research work was to estimate the risk of functional complications arising within thyroid after radiotherapy, when thyroid of patients being ill with carcinoma of head and neck area skin was afflicted with radiation beam as well as to examine whether the circadian rhythmand concentration of hypophysis and thyroid hormones are dependent on combined treatment. The group contained 18 pilot patients treated with combined method, which were examined for concentration and circadian rhythm of TSH, T3, T4, fT3, fT4 three times: before commencement of treatment, one month and six months after completion of treatment. Results of circadian rhythm and concentration of thyroid hormones examinations proved that in case of all hormones the circadian rhythm exist which undergoes a dysrrythmia after one month and six months from completion of combined treatment.

Adult↗
PubMed2000

[Reconstructive methods in the surgery of defects of the floor of the mouth and the tongue due to carcinoma].

A retrospective analysis of patients with tongue, floor of the mouth and tonsil carcinoma treated in II ENT Department University School of Medicine in Zabrze between 1994 and 1996 was undertaken. 32 male and 10 female underwent operation of the oropharynx. The visor flap, mandibulotomy or peroral approach was used. In 32 cases mandibulotomy, in 2 cases visor flap and in 3 cases peroral approach was performed. The usefulness of bone grafts from iliac ala, skin flaps and part of the tongue applied to replace the defect after extensive operation of the oropharynx was analysed and presented. In 2 patients partial mandibulectomy was performed. In 2 patients defect was replaced with iliac crest. Good graft's vitality, availability and function were emphasized.

Carcinoma, Squamous Cell↗
PubMed1998

[Hearing aid fitting in children treated at the Phoniatric Outpatient Clinic in Zabrze in years 1986-1990].

The purpose of this study was to evaluate the hearing aid fitting of 179 regularly controlled, hearing-disabled children from the Silesian area, first time admitted to Phoniatric Outpatient Clinic in Zabrze in years 1986-1990. The mean age of provision of a hearing aid was high. Children were supplied with hearing aids at mean age of 4,9 years (losses > 60 dB) and of 9,3 years (losses < or = 60 dB). There was a delay from 8,4 up to 12,5 months (losses < or = 60 dB) between the age of fitting and the issue of the hearing aid. It was also stated that the total amount of children wearing their aids binaurally decreased significantly from 118 to 74 during 5 years' period. As for the utilisation of hearing aids, prevalence of full-time users (57.9%) was demonstrated in confrontation to non-users (5.6%).

Adolescent↗
PubMed1997

[The case of myoepithelioma of the parotid gland].

Myoepithelioma of the parotid gland occurs relatively rarely. In the literature was described only 33 cases of this tumors. It's growth's slow and distension. Basing upon the case of 48-year old woman, the authors discuss the difficulties of diagnostic, treatment and the course of the disease.

Female↗
PubMed1996

[Gentamycin as a cause of hearing impairment in children treated at the Phoniatric Outpatient Clinic in Zabrze between 1987-1992].

Medical history was analyzed in an attempt to identify the etiology of 748 hard-of-hearing children treated at the Phoniatric Out-Patient Clinic in Zabrze between 1987-1992. In 198 cases, gentamicin was the major cause of bilateral sensorineural hearing loss. Ninety children had a hearing loss of less than 60 dB and 108 above 60 dB. The results obtained in our study are comparable to those of other authors.

Child↗
PubMed1995

[The evaluation of the wound healing failure in patients after total laryngectomy].

The authors presented own results concerning complications in wound healing after total laryngectomies. 59 total laryngectomies and 4 pharyngo-laryngectomies were performed. In 18 cases local and systemic complications were observed. Pharyngo-cutaneous fistulas developed in 15 patients. Therapeutic management was successful in all cases.

Adult↗
PubMed1995

[A case of lightning resulting in ear burn].

The authors described a rare case of 13 years old girl burnt by lightning. The burns of the skin of neck, perforation and destruction of the handle of malleus were stated. No internal ear injury was observed.

Adolescent↗