PubMed Health⌕ Search

Biomedical subjects

E D Cook

Publications and source records attributed to E D Cook.

7 recordsLinked to original sources
PubMed1999

Genetics and the British insurance industry.

Genetics and genetic testing raise key issues for insurance and employment. Governmental and public concern galvanised the British insurance industry into developing a code of practice. The history of the development of the code, issues of genetic discrimination, access to medical information, consent and the dangers of withholding information and the impact on the equity of pooled risk are explored. Proactive steps by the Association of British Insurers suggest that moral reflection not legislation is the way forward.

Disclosure↗
PubMed1999

Practical considerations in the analysis of complex sample survey data.

Large scale sample surveys often provide fertile ground for analyses by epidemiologists. Recently, survey organizations such as the National Center for Health Statistics and the United States Bureau of the Census have distributed data from large surveys to interested investigators via CD-ROM. Confronted by the richness of such databases and the historic relative lack of availability of suitable software to appropriately account for the survey design, researchers have often simply ignored the complexities of the survey and analyzed the data as if they resulted from a simple random sample. The availability of modern programs such as STATA and SUDAAN provides data analysts with the new analytical capabilities to perform design-based analyses whenever appropriate. We used data from the NHANES III and the PAQUID study to illustrate the ease of performing design-based analyses. We also compared results of analyses under both model-based and design-based scenarios. When data from complex sample surveys were analyzed using both model-based and design-based strategies, differences in point estimates and standard errors of means, regression coefficients and odds ratios were found. The differences in regression coefficients and odds ratios between the two strategies were not as great as the differences in means. The potential for differences and the availability of survey analysis software should encourage researchers to use design-based techniques to analyze data from complex sample surveys more appropriately.

Adolescent↗
PubMed1996

The Americans with Disabilities Act: prescription for tax relief.

As employers, healthcare organizations must comply with Title I of the Americans with Disabilities Act of 1990-Employment Discrimination by Private Entities-which covers virtually all aspects of employment and prohibits employers from discriminating against otherwise qualified job applicants and workers who have disabilities or who become disabled. Further, healthcare organizations must comply with the provisions of Title III of the act-Nondiscrimination on the Basis of Disability by Public Accommodations and in Commercial Facilities-which requires places of public accommodations and commercial facilities to be designed, constructed, and altered in compliance with the accessibility standards of the act. While compliance with the ADA can be costly, four specific sections of the Internal Revenue Code offer tax relief to organizations that meet the guidelines of Titles I and III.

Architectural Accessibility↗
PubMed1993

Phonetic and phonological features of approximants in Athabaskan and Eskimo.

The Athabaskan and Eskimo approximants, particularly [j], [w], and [symbol: see text], behave phonologically like obstruents. In both language families, [j], which alternates with a sibilant, is phonologically [+coronal], although its coronality has been questioned on phonetic grounds. These approximants best illustrate Sapir's [1925] notion of 'a true point in pattern' which must be defined 'over and above its natural [phonetic] classification on organic and acoustic grounds'. The fact that approximants are classified phonologically as sonorants or obstruents in different languages is incompatible with the universality of distinctive features and their phonetic properties. This problem is resolved by placing a phonological boundary for [+/-sonorant] somewhat differently in the continuum of the sonority hierarchy, depending on how approximants behave in individual languages.

Female↗
PubMed1987

Nifedipine in the treatment of Raynaud's phenomenon in patients with systemic sclerosis.

A double-blind, placebo-controlled, cross-over trial of nifedipine 10 mg three times daily for 6 weeks, in 10 patients with Raynaud's phenomenon secondary to systemic sclerosis, is reported. A significant reduction in the duration of attacks of Raynaud's phenomenon was observed. Nifedipine therapy also reduced the number and severity of attacks of Raynaud's phenomenon and the development of new digital ulcers, and increased the digital blood flow, but none of these changes was statistically significant. No alteration in red blood cell deformability or leukocyte chemiluminescence was observed during nifedipine treatment.

Blood Flow Velocity↗
PubMed1985

Physician utilization of pharmacy computer drug profiles.

A pharmacy computer medication profile is a valuable tool for the management of drug resources, proper utilization of physician time, and improvement in patient care by drug compliance monitoring. In an effort to reduce medication stockpiling, improve patient compliance, and reduce drug abuse, a system of preparing computer printouts of patient medication profiles was developed. The profile is placed in each patient's chart prior to each visit with the physician. This profile can then be used by the physician to identify drug compliance and abuse problems.

California↗