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Biomedical subjects

E D Frank

Publications and source records attributed to E D Frank.

At least 19 recordsLinked to original sources
PubMed1995

Superior hypogastric plexus block for chronic pelvic pain in the presence of endometriosis: CT techniques and results.

PURPOSE: To evaluate the use of superior hypogastric plexus block with computed tomographic (CT) guidance in patients with endometriosis and chronic pelvic pain. MATERIALS AND METHODS: Seven blocks were performed on an outpatient basis in five women with endometriosis and pelvic pain. In the first four patients, one or two 20-gauge, 15-cm needles were placed anterior to the spine at the common iliac bifurcation from a posterior approach. In the fifth patient, the block was performed from an anterior approach with a single needle. RESULTS: One procedure resulted in mild pain relief, three in considerable pain relief, one in complete midline pain relief with no change in the lateral pain, and one in complete pain relief. One procedure was terminated because anesthetic was injected into the peritoneal cavity. There were no other complications. CONCLUSION: CT-guided superior hypogastric plexus block is easily performed and can be used to assess whether chronic pelvic pain can be attenuated by blocking the superior hypogastric plexus.

Adult↗
PubMed1983

Shaped, lead-loaded acrylic filters for patient exposure reduction and image-quality improvement.

Shaped filters that are constructed of lead-loaded acrylic material for use in patient radiography are discussed. Use of the filters will result in improved overall image quality with significant exposure reduction to the patient (approximately a 2X reduction in breast exposure and a 3X reduction in thyroid gland exposure). Detailed drawings of the shaped filters for scoliosis radiography, cervical spine radiography, and for long film changers in special procedures are provided. The use of the scoliosis filters is detailed and includes phantom and patient radiographs and dose reduction information.

Acrylic Resins↗
PubMed1981

Aortic smooth muscle cells contain vimentin instead of desmin.

The 10-nm filament subunit proteins of smooth muscle cells in the mammalian aorta were analyzed by immunofluorescence and by two-dimensional gel electrophoresis. Indirect immunofluorescence studies on frozen sections of aorta showed intense staining of the tunica media by antibodies to vimentin, whereas no reaction could be detected with antibodies to desmin. Crude preparations from the tunica media contain a protein with molecular weight and isoelectric point similar to those of vimentin. Desmin was not detected on these same two-dimensional gels. We conclude that aortic smooth muscle cells contain vimentin as the predominant form of 10-nm filament protein subunit, unlike other muscle cells in which desmin predominates. Other immunofluorescence results indicate that the aorta may differ from smaller blood vessels which appear to contain both desmin and vimentin.

Animals↗
PubMed1979

The detection of smooth muscle desmin-like protein in BHK21/C13 fibroblasts.

Three distinct proteins, actin (42,000 daltons), the principal form of fibroblast 10 nm filament protein (55,000 daltons), and a protein with a molecular weight of 52,000 and a pI of 5.8 were detected in nonionic detergent-insoluble cytoskeletal and 10 nm filament preparations of control BHK21/C13 and line 9 hamster fibroblasts. Cytoskeletal preparations of other hamster fibroblast cell types, such as NIL8 and primary embryo fibroblasts, contained the 55,000-dalton component but lacked the 52,000-dalton protein. A Rous sarcoma virus transformant of the BHK21/C13 line and an adenovirus transformant of line 9, resembled the NIL8 and other fibroblast types in that they contained only the 55,000- and 42,000-dalton polypeptides. The identity of the 52,000-dalton protein in BHK21/C13 cells was studied. This protein co-electrophoreses on both one- and two-dimensional polyacrylamide gels with the predominant muscle form of 10 nm filament protein. Further, one-dimensional peptide maps of the hamster smooth muscle 10 nm filament protein and the hamster fibroblast 52,000-dalton protein are identical to one another and distinct from the peptide maps of both the 42,000- and the 55,000-dalton components of the fibroblast cytoskeletal preparations. We conclude that BHK21/C13 cells contain both the fibroblast and the muscle form of 10 nm filament protein.

Animals↗
PubMedDate not supplied

Radiography of the ankle mortise.

Radiographers often use methods to position the ankle that produce inaccurate images of the ankle mortise. This article describes a technique using a 15 degree to 20 degree internal-oblique position of the leg and foot to demonstrate the ankle mortise radiographically. A textbook protocol also is included.

Ankle Joint↗
PubMedDate not supplied

Interpleural bupivacaine for postoperative analgesia following cholecystectomy: a randomized prospective study.

The effect of interpleural analgesia on postoperative hospital course was analyzed ina prospective randomized study of patients undergoing cholecystectomy. Control patients were treated in the standard manner with systemic narcotics alone; catheter patients had an interpleural catheter placed at the end of surgery and, in addition, could receive systemic narcotics if necessary. The catheter group received interpleural 0.5% bupivacaine with epinephrine every six hours for a total of four injections. Thirteen patients were in each group. Pain score, pulmonary function and narcotic requirement were measured over the first postoperative day. Catheter patients had a lower average pain score (visual analog scale (VAS), 3.6 versus 5.2), decreased narcotic requirement in the recovery room and improved oxygen saturation (96% versus 93%). However, there was no statistical difference in amount of morphine (catheter, 25 +/- 14 mg; control, 31 +/- 15 mg), number of narcotic injections (catheter, 3.8 +/- 1.5; control, 3.5 +/- 1.5), forced vital capacity (catheter, 44% preoperative control, 41% preoperative), recovery room time (catheter, 129 +/- 54 minutes, control, 117 +/- 39 minutes) or total hospital stay (catheter, 4.1 +/- 0.9 days; control, 3.7 +/- 0.8 days). Analysis of hourly VAS scores following a bolus indicated that the analgesia disappeared within approximately four hours. The mean time to a request for narcotic following a bolus was 4.2 hours (excluding 17 of a potential total of 52 instances when narcotic was not requested at all). Therefore, the duration of pain relief for subcostal incisions using interpleural 0.5% bupivacaine is approximately four hours.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMedDate not supplied

Scatter radiation.

Explore the source record for details and available documents.

Absorption↗