[Short-term induced hyperglycemia in the combined treatment of locally infiltrating forms of cancer of the breast].
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Biomedical subjects
Publications and source records attributed to E D Lobanova.
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In vitro bacteriological investigation of various pathological materials revealed the main etiological profile of purulent complications in patients with chronic renal insufficiency before and after allotransplantation of the kidney. A statistically significant magnitude of the frequency of detecting identified pathogens in patients wit renal insufficiency is presented. Phage typing of pathogenic staphylococci isolated from patients with chronic renal insufficiency and from patients after kidney allotransplantation revealed no correlation in belonging of the isolates to a definite phage group in such patients. The effect of semi-synthetic penicillins on gram-positive and gram-negative organisms is estimated. The efficacy of the antibiotic effect on various species of pathogenic micro-organisms isolated from patients with renal affections is shown on the basis of a number of criteria, such as the ranges of the microbial sensitivity, the antibiotic MIC with respect to the majority of the strains, the character of the drug effect.
Determination of bacteriuria, leucocyturia, active leucocytes and Sternheimer-Malbin's cells in patients with transplanted kidneys during the postoperative period provided identification of pyelonephritis in the transplanted kidney. E. coli, Proteus, Staphylococcus, P. aeruginosa and microbial associations were the main causative agents of pyelonephritis in such patients. The majority of the causative agents were polyresistant to antibiotics. Investigation of the microbial sensitivity to antibiotics and determination of their levels in the patients promote development of rational schemes for the treatment of pyelonephritis. Early identification of pyelonephritis of the transplanted kidney and its timely treatment with antibiotics allow avoiding destruction of the transplanted organ and promote its normal functioning.
Antibiotic therapy was effective in the majority of cases with early identified infectious complications after the kidney transplantation. The treatment dose of the antibiotic should be individually corrected for every patient with a transplanted organ with an account of kidney transplant function. When immunodepressants are used in addition to the chemotherapy it is necessary to control the immunological indices.
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