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E D Smirnova

Publications and source records attributed to E D Smirnova.

11 recordsLinked to original sources
PubMed1984

[Intraorgan vascular bed of the transplanted small intestine after spontaneous and surgical restoration of lymph drainage from the transplant].

The model of heterotopic autotransplantation of the small intestine has been made in 83 dogs. In two experimental groups the state of the intraorganic vascular bed of the intestine transplant has been studied at a spontaneous and surgical restoration of the lymph outflow ways from it. The reconstruction of the lymph outflow ways is performed by means of lymphonodulo-noduloanastomoses formed between the mesenteric and iliac lymphatic nodes. The intraorganic vascular bed is studied during 1 day - 1 year by means of polichromic injection of Gerota mass with a subsequent clearance of the preparations after Spaltecholts--Zhdanov. The autotransplantation of the small intestine results in a morphological rearrangement of the intraorganic blood and lymphatic bed of the transplant. In both experimental groups it is unityped and characterized with a dilatation of venous and lymphatic vessels in all layers of the intestine, with a twisted course of the vessels, with destruction of some lymphatic vessels and networks of the lymphatic capillaries. At the spontaneous regeneration of the lymphatic pathways, a longer time is necessary to correct these disturbances (up to 6 months). The surgical restoration of the lymph outflow ways from the intestine accelerates normalization of the vascular bed architectonics in the transplant. The morphological rearrangement of the intraorganic vascular bed of the small intestine is mainly completed in 1 month after autotransplantation.

Animals↗
PubMed1984

[Fat absorption following temporary ischemia of the small intestine].

Ischemia of the rat small intestine lasting 40 min leads to pronounced structural disorders in lipid transport across the enterocytes, reduction in enzymatic activity of the cells and in absorption function, and to the loss of fat with feces. The normalization of the indicated parameters occurs at varying times and ends after 1 month. Fat transport abnormality is marked by an increase in lipid drops in the cavities of the smooth endoplasmic network, appearance of large and numerous matrix lipids, by a greater reduction, as compared to normal, in the membranes of the rough endoplasmic network and lamellar complex in the epithelium of the villi. Accumulation of lipids and retardation of their release from the cytoplasm are determined by incomplete differentiation of the epithelium, which is also combined with a decreased enzymatic activity.

Animals↗