[Immune and hormonal response to dimethylnitrosamine].
The study was concerned with assay of levels of 11- HOCS in blood and adrenal tissues and antibody-producing cells in the spleen as well as spontaneous rosette-formation by blood thymic and splenic lymphocytes in the course of carcinogenesis induced in experimental animals by nitrosodimethylamine treatment. Heightening of adrenal cortical function was registered at two stages: at an early stage of carcinogenesis--two months after nitrosodimethylamine treatment, and during tumor progression--after 7 months. Cellular immunity inhibition was observed at the said periods.
11-Hydroxycorticosteroids↗