A controlled study of the use of autologous platelet gel for the treatment of diabetic foot ulcers.
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Administration, Topical↗
Biomedical subjects
E D'Agostino
Publications and source records attributed to E D'Agostino.
Risk factors in the elderly.
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Journal Article↗
[Assessment of cognitive and functional status in hospitalized elderly].
In 1745 elderly patients (971 men and 774 women), consecutively admitted to University Geriatric Ward in San Giovanni Battista Hospital of Torino, cognitive status (SPMSQ) was evaluated. Moderate-severe and mild cognitive impairment were respectively present in 26.8% and 15.8% of the sample. Subjects affected by moderate-severe cognitive impairment were older (80.7 +/- 8.0 yrs) than patients with mild deterioration (79.5 +/- 7.8 yrs) and patients without cognitive problems (75.3 +/- 8.3 yrs). The number of pathologies and the length of hospital stay were not related to severe cognitive impairment. Lower schooling was associated with cognitive alteration. Among subjects affected by moderate-severe cognitive deterioration 15.6% was living with assistance before hospitalization. The prevalence of functional impairment (ADL) was higher (70.9%) among patients with moderate-severe cognitive impairment. In-hospital mortality was higher (21.2%) among patients with moderate-severe cognitive deterioration.
Activities of Daily Living↗
Absorption of lidocaine following subarachnoid and epidural administration.
The absorption of lidocaine into the vascular system from the epidural and subarachnoid spaces was determined in 20 patients. Seventy-five milligrams (1.5 ml of a 5% solution) of lidocaine was administered intrathecally to 10 patients for spinal anesthesia and 75 mg (3.75 ml of a 2% solution) was injected epidurally. Venous plasma levels of lidocaine were determined at 2, 5, 10, 15, and 30 minutes after subarachnoid or epidural injection. No significant differences existed between the maximum venous plasma concentrations of lidocaine following epidural injection (0.41 +/- 0.07 microgram/ml) and following subarachnoid injection (0.32 +/- 0.07 microgram/ml). However, the rate of vascular absorption of lidocaine from the subarachnoid space was significantly slower than from the epidural space. By 2, 5, and 10 minutes after injection, venous plasma concentrations of lidocaine were significantly higher following epidural injection than they were after subarachnoid injection. This variation was not attributable to differences in blood pressure folloiwng injection. The differential rate of absorption is probably related to the anatomical arrangement of the venous plexuses in the epidural and subarachnoid spaces.
Absorption↗