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Biomedical subjects

E Daberkow

Publications and source records attributed to E Daberkow.

4 recordsLinked to original sources
PubMed1993

Cardiopulmonary function in men with sickle cell trait who reside at moderately high altitude.

Sickle cell trait has been associated with an unexplained increased risk of sudden death during military basic training. Previous studies of cardiopulmonary function in persons with sickle cell trait at sea level or after brief exposure to moderately high altitude have not shown significant abnormalities. To determine whether cardiopulmonary function is impaired in men with sickle cell trait who chronically reside at moderately high altitude, we prospectively studied 17 men with sickle cell trait and 25 men with normal hemoglobin. All subjects had resided at > or = 1609 m above sea level for at least 10 years. Resting pulmonary function and cardiopulmonary performance during exercise to exhaustion were evaluated. No statistically significant differences were observed between subjects with sickle cell trait and controls for any of the resting pulmonary function variables measured. All parameters of exercise performance were not statistically different between the groups. Increasing age was associated with a similar decrease in work capacity and oxygen consumption in both groups. Electrocardiogram findings were not statistically different between groups. We conclude that chronic exposure to moderately high altitude does not impair cardiopulmonary function in men with sickle cell trait.

Adult↗
PubMed1992

Maximal voluntary exercise variables in children with postoperative coarctation of the aorta.

Thirty-one children with postoperative coarctation of the aorta underwent maximal graded bicycle ergometry using an electronically braked ergometer and the James protocol; 18 also underwent expiratory gas measurement using a mass spectrometer. Twenty-two age- and gender-matched normal subjects were used as a control group. The mean age at operation was 41 months and the mean age at evaluation was 134 months (mean follow-up interval 93 months). The original surgical repair was subclavian flap repair in 8 patients, end to end anastomosis in 21, patch aortoplasty in 1 patient and tubular graft in 1. Patients exercised until exhaustion and maximal exercise variables were obtained. The maximal voluntary peak heart rate was 183 beats/min (94.6% of predicted value), indicating excellent effort. Mean power was 111% of predicted value and, when measured, maximal oxygen consumption was 89% of predicted value with an anaerobic threshold at 63 +/- 3.5% of exercise time. The observed work variables were not different from values in the control group and were not affected by the type of repair. The mean peak systolic blood pressure was 152 +/- 7.6 mm Hg versus 147 +/- 5.7 mm Hg in the control group (p = NS). Patients who had associated intracardiac lesions had significantly lower maximal oxygen consumption (85 +/- 3% vs. 98 +/- 4% of predicted value). The results suggest that adequate cardiopulmonary function, normal or above average work capacity and normal exercise systolic blood pressure can be obtained in children with satisfactory repair of coarctation of the aorta performed before school age.

Adolescent↗
PubMed1992

Permanent pacemakers in children.

Care of children with permanent pacemakers requires sophisticated nursing knowledge and skills. The tremendous advances in pacemaker technology and complexity of modern pacing provide challenges for nurses caring for these children and their families. Knowledge of pacing physiology, components of the pacing system, indications for pacing, post-pacemaker implant care, trouble-shooting of pacemaker problems, child and family teaching, and long-term follow-up is necessary for provision of safe, effective nursing care.

Adolescent↗