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Biomedical subjects

E Darre

Publications and source records attributed to E Darre.

31 records · Page 2Linked to original sources

Elephantiasis neuromatosa. A light, immunohistochemical and electron microscopic study.

An example of elephantiasis neuromatosa, an unusual variant of neurofibromatosis, coexistent with lipomatosis is presented. This dual cell population produced a diffuse swelling of the gluteal sulcus of a young female. The neurogenous origin of the spindle cell component was substantiated by immunoreactivity for S-100 protein as well as by the fine structural observation of a regular basement membrane coating and a profusion of Luse bodies. As far as can be ascertained, this is the first reported immunohistochemical and ultrastructural study of this particular variant of peripheral nerve sheath lesion.

Adolescent↗

Contact dermatitis to methyl methacrylate.

2 cases of contact dermatitis to methyl methacrylate monomer are presented. The patients are nurses who mixed bone cement at orthopedic operations. During the procedure, they used 2 pairs of gloves (latex). Butyl rubber gloves are recommended for methyl methacrylate monomer to avoid sensitization and/or cumulative irritant contact dermatitis on the hands.

Adult↗

Surgical rubber gloves impervious to methylmethacrylate monomer.

Conventional surgical rubber gloves are permeable to the methylmethacrylate monomer (MMM) of acrylic bone cement. An in vitro technique was used which proved butyl rubber gloves, 0.48 mm thick, to be impervious to MMM. to avoid sensitization, butyl rubber gloves may be recommended to persons who are in contact with MMM. Such gloves should be worn by persons with known contact sensitization to MMM.

Bone Cements↗

The use and handling of acrylic bone cement in Danish orthopaedic departments.

In order to evaluate the use and handling of acrylic bone cement, questionnaire were presented to all Danish orthopaedic departments in 1987 and again in 1992. Marked improvements in the environmental safety precautions for handling of bone cement had taken place during the 5-year period. In 1992, the intraoperative handling and use of bone cement is thus generally considered safe. Further improvements are still to be advocated in some departments. The exposure to methylmethacrylate monomer (MMA) vapour during the cementation procedures should be eliminated by local punctual field suction or change to a bone cement with a lower content of monomer (MMA/n-decylmethacrylate/isobornylmethylacrylate bone cement). Unnecessary manual contact with the cement should be avoided, and if contact is necessary, special protective gloves (butyl rubber gloves or 4H-gloves) should be used in addition to ordinary surgical gloves.

Air Pollutants, Occupational↗