Biomedical subjects
Publications and source records attributed to E De Sutter.
In cooperation with the C.H.U.-Lille (Eye Department) we set up an interregional and european project. We explain the possibilities and difficulties of remote diagnosis. The aim is to build up a network between different ophthalmological centers and so to give access to different centers of expertise to have a faster and more reliable diagnosis for the benefit of the patient.
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We reanalysed the current staging systems for retinoblastoma, the classification of retinoblastoma for prognosis by Reese and Ellsworth and the new Essen prognosis classification for conservative sight-saving therapy by univariant analysis. We compared the value of those classifications with one another.
The retinoblastoma is the most frequent intraocular tumour in early childhood occurring in a hereditary as well as non-hereditary form and showing an increasing incidence since the beginning of this century, which has nowadays stabilized near 1/16,000. Further differentiation is necessary in view of unilateral and bilateral as well as sporadic and familiar occurrence. Estimates of the relative frequencies of the resulting different groups are given und summarized in two tables in two different aspects.
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105 patients with retinal detachment were HLA types and divided into hyperopic, emmetropic and myopic groups. None of these different groups showed a statistically significant correlation with any of the HLA antigens. For the patient group as a whole, there was a slightly significant correlation with HLA-B8 at the corrected p level of 0.05.
An 11p interstitial deletion is reported in a severely mentally retarded boy with aniridia, genito-urinary anomalies, and distinct craniofacial dysmorphism. At the age of 4 years a large Wilms' tumor of the right kidney was diagnosed.
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