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Biomedical subjects

E DeRenzo

Publications and source records attributed to E DeRenzo.

2 recordsLinked to original sources

Rat sciatic functional index data management system with digitized input.

Quantification of the functional condition of rat sciatic nerve is an important experimental procedure. In the present study, a system for management of the sciatic functional index ( SFI ) data is described. Results obtained with the Sciatic Index Management System (SIMS) were compared with results obtained with other measurement techniques. Validity and reliability of the SIMS were found to be excellent, and speed of data analysis was increased. It is concluded that the SIMS represents a significant advance in the quantification of nerve regeneration data.

Animals

Development of differences in response latencies to right and left visual fields.

Robust lateralization developed in right-handed adults who were asked to judge letter pairs as "same" or "different" during 4608 trials. By the end of the first two blocks (768 trials) "same" responses were favored when presented in the RVF (transmitted directly to the left hemisphere) and "different" responses were favored when presented in the LVF (transmitted direction to the right hemisphere). This gradually reversed over sessions with "same" responses becoming faster for letters presented in the LVF, and "different" responses becoming faster for stimuli presented in the RVF. The laterality acquired under these conditions was cumulative and reproducible, appeared in all 16 subjects, and was preserved between sessions a week apart. The data suggest that laterality is a flexible and reversible characteristic of the human brain even when stimulus and task remain constant.

Discrimination Learning