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E Diaconu

Publications and source records attributed to E Diaconu.

9 recordsLinked to original sources

[Some technical considerations on partial nephrectomy (author's transl)].

After some considerations on the problems of operation technique which are raised up by partial nephrectomy, the authors review its' indications. After presentation of the clinical experience based on ten cases of partial nephrectomy, carried out during the years 1972-1974, of which 7 were for lithiasis, 2 for renal tuberculosis and one for a solitary renal cyst, the authors advise primary ligature of the segmental vascular pedicle, whenever possible and use of the perinephretic fat to cover over the sectioned surface, as it has strong hemostatic action, good tolerance and that owing to this, nephropexy is carried out.

Humans

[Pharmacological studies of sulbactam and its association with semisynthetic beta-lactam antibiotics].

The acute toxicity, local tolerance and pharmacokinetic properties of sulbactame manufactured by the Iaşi Antibiotic Investigation Centre, alone or in association with ampicillin or amoxicillin were tested. Some tests were made comparatively with the product Unasyn--Pfizer. The obtained data show that this beta-lactamase inhibitor has a low toxicity--DL50 i.p. in mice over 4,000 mg/kg, both alone or associated with the two semisynthetic beta-lactamic antibiotics. The local tolerance is good and the serum levels of the above mentioned associations are above towards the tested bacteria and are similar or very close to those of Unasyn. It is believed that the therapeutical use of the association sulbactame + ampicillin or sulbactame + amoxicillin is very useful in the beta-lactamase producing germs infection.

Amoxicillin