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Biomedical subjects

E Dias

Publications and source records attributed to E Dias.

27 records · Page 2Linked to original sources
PubMed1979

Breeding studies reveal segregation of a canine Robertsonian translocation along Mendelian proportions.

Six matings of golden retriever-type mongrel dogs with a 13/23 Robertsonian translocation were studied. Three matings between normal dogs and dogs heterozygous for the translocation produced 12 normals and 11 heterozygotes. In three matings between heterozygotes, the distribution of normal, heterozygous, and homozygous proteny was Mendelian (8:12:5). No gross phenotypic anomalies were observed with the exception of congenital inguinal hernia in two female homozygotes. Nondisjunction in the form of trisomic or monosomic individuals for either autosome 13 or 23 was not observed.

Animals↗
PubMed1978

Centric fusion of autosomal chromosomes in a bitch and offspring.

A fertile Golden Retriever cross had a chromosome number of 77, with 3 large metacentric chromosomes representing the 2 X chromosomes and a centric fusion of 2 autosomes. The known reproductive history of the bitch included litters of 6, 5, 13, and 10 pups during 4 consecutive estrous cycles. A total of 16 pups and their sire were located and karyotyped. The sire and 9 of the pups were of normal karyotype. Seven of the 16 pups were found to be carriers of the translocation. The translocation was determined to be a fusion of chromosomes 13 and 17, utilizing G-banding techniques. Although centric fusion has been reported in dogs with congenital disease, the dogs in the present study were not phenotypically unique or abnormal.

Animals↗
PubMedDate not supplied

[Histometric study of age related changes of elastic and collagenous fibers in the aortic arch of Meleagris gallopavo L., 1758, of both sexes (author's transl)].

The authors have studied the quantitative variation of elastic and collagenous fibers in the aortic arch of Meleagris gallopavo (turkey), both sexes, from 1 up to 180 days old. An histometric method was employed using as integrating eyepiece for the countings. The results show that the concentration of elastic fibers increase from the first to the 45th day, decreasing from this point until the age of 180 days, while that of collagenous fibers increase from the first until the last etary group studied.

Age Factors↗
PubMedDate not supplied

[Doppler echocardiography in the diagnosis of mechanic complications of acute myocardial infarction].

OBJECTIVES: To evaluate the ability of bedside emergency Doppler/Echocardiographic (ECOCG/DP) studies in the diagnosis of mechanic complications during acute myocardial infarction (AMI). DESIGN: Retrospective analysis of 44 fatal AMI cases, studied by ECOCG/DP and with diagnostic confirmation by surgery and/or necropsy. SETTING: Patients (pts) with AMI admitted to an Intensive Care Unit of a tertiary Hospital (UCIM), Hospital de Santa Maria. PATIENTS: 44 fatal AMI cases were analysed (24 men and 20 women; mean age +/- SD: 72 +/- 9 years) and were divided in two groups according to Killip classification in Group 1 (III/IV): 35 pts and Group 2 (I/II): 9 pts. METHODS: ECOCG/DP was performed in a routine basis at admission, using all standard views and by subcostal view when in an emergency scenario. RESULTS: In 20 pts with bad left ventricular function (LVF) (Group 1) at admission, ECOCG/DP monitoring showed that death was due to worsening of LVF, which was confirmed by necropsy. In the other 15 pts of this group, ECOCG/DP documented the clinical diagnosis of cardiac rupture (free wall: 4 pts; papillary muscle: 4 pts; interventricular septum: 7 pts) which was confirmed by surgery and/or necropsy. In the 9 pts of Group 2, ECOCG/DP disclosed, at admission, good LVF in all. In 5 pts there was a sudden worsening clinical status, and ECOCG/DP showed a severe pericardial effusion with right chambers collapse, highly suggestive of free wall rupture also confirmed at necropsy. In the other 4 pts, ECOCG/DP showed aggravation of wall motion abnormalities and of LVF without rupture, once again in agreement with necropsy. Five clinical cases are presented for illustration of this issue. CONCLUSION: In the 44 fatal AMI cases of our study there was complete agreement between the ECOCG/DP and necropsy studies. In AMI patients, ECOCG/DP monitoring can in a routine basis, evaluate wall motion abnormalities and LVF. In an emergency setting ECOCG/DP can diagnose all the mechanic complications with a great certainty.

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