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Biomedical subjects

E Diem

Publications and source records attributed to E Diem.

At least 19 recordsLinked to original sources
PubMed1995

[Pyoderma gangrenosum as a precursor of myeloid leukemia].

A 34-year-old woman who was 20 weeks pregnant developed pyoderma gangrenosum while receiving treatment for infarct pneumonia. Because of her septic condition an abortion was performed. The patient received intravenous prednisolone as a pulse treatment for her pyoderma gangrenosum, which was followed by oral methylprednisolone and oral dapsone for 6 weeks. After dose reduction the patient had a severe relapse. The steroid dose was increased and dapsone was replaced by cyclosporin A. The smaller ulcers healed spontaneously, but skin grafting had to be performed for the large ulcer. The steroid therapy was tapered and discontinued. Cyclosporin A was continued for 10 weeks as monotherapy. Subsequently, the patient was free of symptoms for 7 months. Twelve months after the diagnosis of pyoderma gangrenosum the patient developed acute myeloid leukaemia accompanied by a recurrence of the skin disease.

Adult↗
PubMed1995

Health concerns of adolescent girls.

An anonymous self-report questionnaire designed to assess adolescent girls' health concerns was administered to 1,416 female students in grades 7-10 from 38 schools in northwestern Ontario. Results indicated that the future and items of appearance were of the highest level of concern in the sample. Factor analysis of the 27 concern items produced grouping of concerns into four factors: risk-taking behavior, appearance, health promotion/future orientation, and psychological functioning. Comparison of the four factors across grades revealed that concern about risk-taking behavior and psychological functioning did not change; concern about health promotion/future orientation issues decreased as the grade increased; and concern about appearance increased as the grade increased. It is anticipated that the grouping of concerns and differences by grade revealed in this study will assist in designing pertinent health programs to interest and motivate the teenage female population.

Adolescent↗
PubMed1994

[Schoenlein-Henoch purpura associated with chronic post-traumatic osteomyelitis].

In Schönlein-Henoch purpura, a distinctive form of leucocytoclastic vasculitis, immune complex deposits in vessel walls characteristically contain IgA. Complement activation, neutrophil chemotaxis and the subsequent destruction of vessel walls make up the pathologic substrate behind the clinical symptoms, which are characterized by palpable purpura lesions, renal and gastrointestinal symptoms and arthralgias. Viral infections, malignant neoplasms and drugs, but especially streptococcal infections, are incriminated as possible causes of the disease. A case of Schönlein-Henoch purpura associated with chronic osteomyelitis is described. It is note-worthy insofar as there is only one similar case reported in the literature.

Chronic Disease↗
PubMed1993

[Basalioma].

The basal cell carcinoma (BCC) is one of the most frequent tumours. The entire destruction of the BCC is the aim of the therapy. The different methods of treatment have to respect the biological type, the histologic form of the BCC. Tumours at critical localizations (face, hands and feet) should be controlled microscopically, if the tumour has been excised totally. By the microscopic control fatal destructive recurrence can be avoided. The dermatologic treatment of BCC offers different methods in respect to the biological type and localization of BCC and also in respect to the age of the patient.

Basal Cell Carcinoma↗
PubMed1990

[Standardized therapy concepts in circumscribed burns. Wishes and reality!].

The vast majority of minor burns requiring treatment are best managed by clear rational concepts of therapy. If these burns are either treated less than optimal or overtreated, complications like infections or delayed wound healing may ensue. In order to draw conclusions from data obtained in studies on patients with minor burns, we need cohort studies making use of clearly defined therapeutic concepts.

Burns↗
PubMed1990

[Wound myiasis. Facultative myiasis].

Two cases of traumatic myiasis, one in Bowen carcinoma and one in chronic leg ulcer, are described. The maggots isolated were reared to the adult stage; they proved to be Calliphoridae of the genus Lucilia (presumably L. sericata). The various forms of myiasis and the species involved in such parasitism are described, and the therapeutic efficiency of proteolytic enzymes and the necrolytic potency of maggots are briefly discussed.

Adult↗
PubMed1989

[Embolization therapy of cavernous hemangiomas].

Hemangiomas are the most frequent tumors found in newborns, but mostly regress by the age of 7. Spontaneous progression and such complications as hemorrhage, disseminated intravascular coagulation (Kasabach-Merritt syndrome), threatened cardiovascular decompensation, and threatened interference with vital functions are rare and must be treated. Embolization therapy is a new therapeutic approach: vascular malformations and hemangiomas with pronounced arteriovenous shunts are treated by selective arterial embolization of the most peripheral branches of the supplying blood vessels. In contrast, lesions with a steady, slow blood perfusion can be treated by direct embolization of the cavernous system; further thrombosis and organization of the thrombus may lead to a permanent and complete occlusion of the hemangioma. If permanent occlusion cannot be achieved, temporary or partial thrombosis may allow curative plastic or reconstructive surgery, which would otherwise be impossible.

Bucrylate↗
PubMed1988

[Penicillin-induced acute renal failure as a rare severe complication of erysipelas treatment].

Penicillins are the most commonly used antibiotics in dermatology owing to their bacteriocidal effect and the high responsiveness of most bacterial dermatoses to penicillin treatment. Although there is a wide range of adverse reactions to penicillins, severe complications are seen very rarely. We report on two cases of penicillin-induced acute interstitial nephritis and summarize the characteristic features of this serious adverse reaction to penicillin administration.

Acute Kidney Injury↗
PubMed1988

[Cholesterol embolization following anticoagulant treatment].

A 65-year-old female patient with pulmonary embolism developed widespread, extremely painful hemorrhagic necroses of the skin and subcutaneous tissue of the lower extremities 5 weeks after initiation of anticoagulation therapy. Due to the clinical and histopathologic findings and the course of the disease, a diagnosis of cholesterol embolization was made. The characteristic features of this clinical entity and differential diagnostic considerations are discussed.

Aged↗
PubMed1987

[Lymphomatoid granulomatosis].

We present two patients with lymphomatoid granulomatosis (LG) which was diagnosed from the histopathology of cutaneous lesions. Combined cytostatic and corticosteroid treatment induced transient, partial remission in one case, but a lethal outcome could not be prevented in either case. Monoclonal-antibody typing of lesional infiltrates indicated that LG is a malignant T-cell lymphoma.

Aged↗
PubMed1986

Timentin in the treatment of invasive burn wound infection with sepsis.

Twenty-one patients with infected burns were treated with 5.2 g Timentin (ticarcillin 5 g + potassium clavulanate 200 mg) three times a day for an average of 8.3 days. Staphylococcus aureus was the commonest pathogen, there being ten cases of septicaemia with this organism and all were cured. Three patients with Pseudomonas aeruginosa septicaemia and infections with methicillin-resistant S. aureus failed. No drug related side effects were noted.

Adult↗
PubMed1986

[Pemphigus vulgaris--malignant course].

A 42-year-old woman with extensive pemphigus vulgaris failed to respond to high-dosage systemic steroids, immunosuppressive drugs and plasmapheresis. The treatment resulted in severe depression of the immune system, without marked effect on the disease activity. Eleven weeks after onset of disease she died of pneumonia and sepsis.

Adult↗
PubMed1985

Toxic epidermal necrolysis due to antiepileptic therapy in an 8-year-old boy.

Toxic epidermal necrolysis (TEN) has rarely been documented in children. We treated an 8-year-old boy who developed generalized blistering dermatosis after anticonvulsive therapy with diphenylhydantoin. The diagnosis was proved by exfoliative cytology, histology, and electron microscopy. The disease entity and its differentiation from staphylococcal scalded-skin syndrome and toxic shock syndrome are reviewed.

Adult↗