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E Dimitrova

Publications and source records attributed to E Dimitrova.

At least 37 records · Page 2Linked to original sources
PubMed1989

Descriptive epidemiology of childhood malignancies in Slovakia.

Over the period from 1978 to 1984, 673 neoplastic diseases were ascertained in boys and 517 in girls below the age of 15 years in the population-based cancer registry of Slovakia, giving average annual incidence rates of 142.7 and 114.2, respectively, per million population. With the large use of a standard international classification based on cell morphology, an analysis of very detailed structure of these tumors could be performed. Leukemias, tumors of the nervous system and lymphomas were responsible for nearly 70% of all malignancies in childhood during the period studied. Important increase of the total cancer incidence in boys accompanied only by its slight growth in girls during the longer period 1968-1984 was observed. The decline of the total childhood cancer mortality in Slovakia was less rapid than that observed in recent decades in some developed countries. These findings indicate at least the real existence of opportunities for the reduction of mortality from cancer in childhood in this country, too, obviously by a more effective and general application of actually available methods of treatment.

Adolescent↗
PubMed1989

Trends and patterns in cancer incidence in Czechoslovakia, 1968-1985.

Cancer incidence rates and trends in Czechoslovakia investigated in the present study are based for the first time on valid data derived mainly from population-based cancer registries. All rates were age-adjusted using world standard population as a reference. The results confirmed first of all a real and apparent increase of the whole cancer incidence trends which was more expressed in males. The increase in the overall cancer incidence among males could be attributed to the steadily continuing growth of lung cancer, responsible for one-quarter of all new cases in recent years, and to a lesser extent, also to the rising rates of "other skin", prostatic, colonic and rectal cancer. The rates and trends among females were influenced by increase and dominant position of breast and "other skin" cancer, responsible together for one-third of new cases. Increasing trends were observed for the incidence of the uterine body, ovary, and for the great majority of digestive tract and other cancer sites. A reduction of incidence was seen only for stomach in both sexes, for the uterine cervix among females, and lip cancer among males. The actual rates and trends of cancer incidence in Czechoslovakia could be compared with those observed in other developed countries. The usefulness and unconditional necessity of adequately reliable data on cancer incidence for epidemiological research and administration of cancer control is emphasized.

Adult↗
PubMed1988

Trends and patterns in lung cancer incidence in four cities of Eastern Europe, 1971-1980.

The trends of age-adjusted and age-specific lung cancer incidence rates showed over the period of 1971-1980 substantial differences in four selected towns of Eastern Europe. The downward age-adjusted trends in males coincided in Berlin with the possible beginning of their downturn in the whole country, while their decline in both sexes in Bratislava could be related to the change of demographis factors. In the other two towns studied--Cracow and Tallinn--the substantial increase of lung cancer incidence in males corresponded with the similar evolution in both respective countries (Poland and Estonia). The rising trends in females in both mentioned towns could be more or less compared with their dramatic increase in some developed countries. The rising trends of age-specific rates in younger age groups of males do not indicate meanwhile the positive influence of low-tar or filter-tipped cigarettes on lung cancer incidence in males observed recently in some countries.

Adult↗
PubMed1985

Parity and cancer risk in Slovakia.

Mortality data from women aged 45-74 who died between 1968 and 1977 in Slovakia, Czechoslovakia, were used to examine the effect of parity (number of live-born children) on risk of dying from each of 20 common cancers. After controlling for the effects of age and year of death, the effect of parity on risk was statistically significant at the p less than 0.001 level, for cancers of the stomach, liver, gall-bladder, breast, cervix, and ovary; and at the p less than 0.01 level for uterine corpus and brain. No effect of parity was seen for cancer of the colon or rectum. Among parous women the trend relating risk to level of parity was significant at the p less than 0.001 level for cancers of the breast, uterine corpus, ovary and brain; and at the p less than 0.01 level for stomach cancer. The findings relating parity to cancers of the breast and reproductive organs are consistent with previous reports. The associations of parity with cancers of the digestive tract deserve further study.

Age Factors↗
PubMed1985

Epidemiological features of biliary tract cancer incidence in Slovakia.

This descriptive study is based on detailed data of biliary tract cancer incidence in Slovakia in the period 1968-1977. Age-adjusted incidence rates of biliary tract cancer in the given decade decreased in females while in males they showed a slight increase. The study of geographic distribution revealed diminishing incidence rates from west to the east in both sexes with extremely elevated rates in towns and suburban districts in males. Different shapes of age-specific incidence curves together with the identified histological types suggested different epidemiological characteristics of individual subsites within this site. Relatively high incidence rates of biliary tract cancer in Slovakia as well as in whole Czechoslovakia, in comparison with other countries or areas of Europe, could be related to the excessive prevalence of gallstones and high number of surgical interventions upon biliary tract in this country while the decreasing incidence rates in women coincided with elevated number of cholecystectomies. The significance of detailed descriptive data from cancer registries for further analytic and etiologic study of biliary tract cancer according to subsites for a better delimitation of high risk groups and primary prevention strategies is stressed.

Adult↗
PubMed1985

Epidemiologic aspects of malignant skin melanoma in Slovakia.

The trends of age-adjusted incidence rates of malignant skin melanoma in Slovakia from 1968 to 1977 showed important increase with an annual increment of 5.8% in males and 3.2% in females. The mortality rates during this period remained lower and their increase was less expressed. The study of geographic patterns of incidence revealed great variation with highest rates in urban districts. A marked predominance of the primary lesions on trunk in males and on lower limbs in females was observed. The differences in anatomic distribution are demonstrated also in age-specific incidence rates of malignant skin melanoma by main subsites. Intermittent overexposures to the sunlight in connection with rising standard of life and leisure seem to be the most suitable explanation for the rise and subsite distribution and dynamics, as well as the geographic patterns and international position of incidence rates of malignant skin melanoma in this country.

Adolescent↗
PubMed1984

The role of registration in a nationwide cancer control program in Slovakia.

In comparison with the official statistics substantially higher, more reliable and more detailed cancer incidence and mortality rates were ascertained by the National Cancer Registry of Slovakia established in the frame work of a complex cancer control program initiated in Slovakia in 1976. The role of the registry in the evaluation of treatment, planning for material and personal resources, orientation of public education, improved classification of malignancies in childhood, in planning and evaluation of preventive measures as well as its experience with the use of the standard WHO system for cancer registries are described. A more important position for the registry in the continuous evaluation and current orientation of the cancer control program is suggested for the future.

Adolescent↗
PubMed1984

[Use of Nobuto's method for controlling the immune titer of poultry against Newcastle disease].

The use of Nobuto 's method for blood sampling with birds and mammals, using filter paper, suggests various advantages in the practice of serologic investigations. Studies were carried out to determine the immune titer of birds against Newcastle disease. Parallel blood samples were taken routinely and after the method of Nobuto with filter paper. Serologic examination was performed through the hemagglutination-inhibition test, beta procedure, with 10 HAU /0.5 cm3. As many as five parallel experiments with blood samples from birds were conducted within the period of from the 15th to the 40th day following vaccination. The results of HI-tests on filter paper, variants a and b, proved mathematically reliable, coinciding with the HI results with the samples studied with sera (P = 0.05). Further studies of blood samples from birds after the HI, beta micromethod, are currently carried out.

Adsorption↗
PubMed1983

Incidence of childhood tumors in Slovakia.

During the decade 1968-1977 a total of 1488 cases of neoplasms were registered in Slovakia in children aged 0-14 years giving an average annual age-specific rate of 120.7 per million. Tumors prevailed in boys with 131.2 in comparison with girls showing 109.7 incidence rate/10(6). The most common malignancies were leukemias (28.2%), tumors of nervous system (23.9%), lymphomas (14.9%) and Wilm's tumors of kidney (6.7%). The proportion of remaining histologic types was lower. The necessity of the use of standard international classification based on morphology for mutual international comparison of childhood tumors incidence rates as well as for other epidemiological investigations is emphasised.

Adolescent↗
PubMed1983

[Comparison of the indirect enzyme-bound immunosorbent method with the hemagglutination inhibition test in detecting Newcastle disease antibodies in vaccinated chickens].

The sensitivity of ELISA and the hemagglutination-inhibition test was comparatively studied in the demonstration of Newcastle disease antibodies in the sera of 57 vaccinated birds. Differences were established in the antibody titers as demonstrated by the two methods. The sensitivity of ELISA was found to be 100 times higher than that of the HI-test. Discussed is the possible use of ELISA in cases where no antibodies or low-titer hemagglutinating ones are demonstrated via the HI-test.

Animals↗
PubMed1983

Geographic patterns of oesophagus, stomach, colon and rectum cancer mortality in Slovakia.

The deaths caused by the mentioned four basic cancer sites of the gastrointestinal tract represented almost one third of all deaths from cancer in Slovakia during the decade 1968--1977. The age-adjusted rates and trends showed substantial increase of the mortality from colon cancer in both sexes as well as from rectum and oesophagus cancer in men and simultaneously significant decrease of stomach cancer in men and women together with quite unchanged rates of rectum and oesophagus cancer mortality in women during the investigated period. Study of the geographic distribution of standardised mortality rates of these cancer sites revealed the existence of great differences in the frame of the individual sites as well as the tendency of substitute the decreasing mortality rates of stomach cancer with those of colon and rectum especially in the western part of the country. The possible advantages and perspectives of the investigation of the geographic patterns of cancer mortality in adequately great territorial units in this country are discussed.

Colonic Neoplasms↗