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Biomedical subjects

E Domenech

Publications and source records attributed to E Domenech.

23 records · Page 2Linked to original sources

[Hypothermia, respiratory distress and umbilical catheterization as risk factors in necrotizing enterocolitis (author's transl)].

Fourteen patients diagnosed of neonatal necrotizing enterocolitis (NNE) admitted into the neonatal unit since August 1977 are presented. They were matched to a control group of 130 newborn infants born during that same period of time for sex, weight and gestational age. All patients were formula fed except for three who followed mixed feeding. NNE was closely associated to hypothermia (p less than 0.005), respiratory distress (p less than 0.001) and umbilical catheterization (p less than 0.005). Umbilical catheters introduced for reasons other than distress did not increase the incidence of NNE. Low birth weight infants were more frequently affected than those weighing over 2,500 gm (ratio, 27:1). Evolution was lethal in six cases. The remaining eight are presently under follow up with no evidence of disease.

Catheterization↗

[Study of serum copper and ceruloplasmin in the newborn (author's transl)].

Serum samples for copper and ceruloplasmin were measured by atomic absorption spectrophotometry. Peripheral blood samples from 30 children-bearing mothers and umbilical cord samples from their clinically normal full-term products were obtained. Mean serum copper for mothers was 216.23 +/- 49.44 mcg./dl. and that for newborns was 48.87 +/- 7.95 mcg./dl. (p less than 0.001). Maternal ceruloplasmin was 66.53 +/- 8.22 mcg./dl. while values for newborns were 11.6 +/- +/- 3.41 mcg./dl. (p less than 0.001). A significant difference (p less than 0.005) in ceruloplasmin values for newborns with a 38-40 week gestation and those with a 41-42 week gestation, were found. The results are compared with those reported in the literature.

Adult↗

[Iron absorption in low birth weight and anemic infants (author's transl)].

A total of 35 iron balances were performed using a milk formula containing 6.25 +/- 1.23 mcg./dl. of iron. Twenty balances were done during the first 3 days of life (group 1) in low birth weight infants with 36.2 +/- 2.6 weeks of gestation and with birth weights of 2.13 +/- 0.28 kg. Thirteen of these infants received a calcium lactate supplement of 800 mg./kg./day. Ten balances were carried out at 13.9 +/- 4.12 days of life (group II) in LBWI with 36.0 +/- 2.1 weeks of gestation and with birth weights of 2.08 +/- 0.22 kg. Five balances were performed in a heterogeneous group (group III) of patients with iron-deficiency anemia (transferrin saturation: 6.3 +/- 2.9%). In group 1, the absorption coefficient for iron was 48.5 +/- 13.6% and of the 562. +/- 155.9 mcg./kg./day of iron ingested, 577.7 +/- 277.7 mcg./kg./day were retained. There were no statistically significant differences between groups I and II, but there were significant differences for ingestion, excretion and iron retention (p less than 0.001). In group I, iron absorption was not modified by the addition of calcium lactate. There was a positive significant correlation (p less than 0.001) between ingestion and net iron retention in groups I and II. Balances performed on five anemic children showed absorption coefficients of 10.5, 11.5, 41.6, 60.0 and 74.2% respectively. In view of our data, recommendations as to the optimal iron supplementation of cow's milk and as to the most desirable time to initiate it are analyzed.

Anemia, Hypochromic↗

[Larsen's syndrome with associates malformations (author's transl)].

A rare polymalformative syndrome is described, consisting in multiple joints dislocations, peculiar face, deformations of the hands and feet, abnormal pattern of the palms creases and congenital heart defect. New findings not reported before were: choanal atresia, agenesia of the right kidney and gall bladder and hypoplasic male genitals.

Abnormalities, Multiple↗

[Metastasis of bronchogenic lung carcinoma in CNS beginning as sensorineural hearing loss].

We report the case of a patient with metastatic bronchogenic carcinoma whose only initial sign was rapid and progressive neurosensory hearing loss. Magnetic resonance imaging with contrast enhancement yielded the diagnosis. Multiple, morphologically, suggestive lesions in the central nervous system (CSN), particularly the cerebellum and corpus callosum were visible. These lesions had no effect on the internal auditory canal (IAC) or cerebellopontine angle (CPA).

Brain Neoplasms↗