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Biomedical subjects

E Durante

Publications and source records attributed to E Durante.

At least 19 recordsLinked to original sources

[Clinical and instrumental study program of nodular diseases of the thyroid].

Authors have passed from a combined clinical and radioisotopic analysis to an integrated polyinstrumental approach by adding thermography and above all echography. In order to achieve the purpose Authors have confronted in retrospective a "clinico-radioisotopic group" of 103 cases, from 1965 to 1975, and an "integrated polyinstrumental group" of 53 cases, since 1976. Comparing the "clinico-radioisotopic method" with "polyinstrumental approach" the main results could be summarized as follows: the diagnostic specificity improved in benign lesions from 77% to 96%, however in malignant lesions it remained about the same (63%). Considering these results the Authors have subdivided thyroid nodules, mainly based on echography, in two distinct categories with the following orientation: I. Solitary Thyroid Nodule: a) definitely cystic -- demonstrated by echography; b) "cold" -- by conventional scintygraphy; c) "negative" -- by thermography; d) non uptake of tumor seeking radiopharmaceutical. The control, therapy and surveilance of these cases should be limited to needle aspiration of the cystic cavity followed, of course, by citologic examination. This aspirations is both diagnostic and possibly therapeutic. II. Solitary Thyroid Nodule: a) definite solid -- echography; b) "cold" -- convential scintygraphy; c) "positive" --thermography (possibly "negative"); d) non uptake of tumor seeking radiopharmaceutical. Here the therapeutic orientation is clearly surgical.

Cysts

[Current status in transplantation of the endocrine pancreas in the treatment of diabetes mellitus 2. Transplantation of fetal pancreas].

The latest findings support hypotheses that diabetes complications are secondary to metabolic control which current insulin therapy is unable to render constant. Surgical attempts to transplant the pancreas and Langerhans islets in the treatment of diabetes mellitus are reviewed and special attention paid to the use of the foetal pancreas which has proved particularly suitable in preventing microangiopathic complication. Comments are based on a careful review of the literature, made in the light of personal experience.

Animals

[Contrast of the grey scale and stable B-scan in the ultrasonic visualization of the thyroid gland].

Thyroid echography can be profitably performed with the stable contrasted B-scan and the gray scale. Both methods are based on the possibility of recording weak echoes from structures inside the gland and so differentiate almost all lesions in a reliable manner. The echo-structural patterns permit the following distinctions to be drawn: uniform distribution of echoes in the normal, hypoplastic and hyperplastic-hypertrophic thyroid. Calcified areas in goitre give distinct, strong echoes, whereas in colloid-cystic goitre there are weak echoes mixed with small empty areas due the cysts. Cystic lesions, too, have empty areas that are well defined, with reinforcement of the posterior wall. In adenoma, there is a uniform, solid area, in which the echoes are evenly distributed internally and the borders are well defined with respect to the unimpaired parenchyma. In acute thyroiditis, the presence of oedema and areas of fibrosis offer sufficiently indicative signs. In tumours, the most typical features are the irregularity of the walls, the distinct attenuation of the beam and the presence of a few, irregular internal echoes. These pictures are almost always peculiar to each situations and thus make echographical investigation of thyroid not only useful, but also indispensable.

Humans

[Stable contrast B-scan in thyroid diagnosis].

A new technique of bidimensional reproduction (B-Scan) is proposed. This is based on successive impressions on the same photogram of the same sections carried out at different amplification and on different frequencies. Frequency and amplification variations are based on constant A-Scan control for the bidimensional detection of echoes which at low frequency and weak amplification are not memorized.

Amplifiers, Electronic

[Echography in the diagnosis of aneurysms of the abdominal aorta].

The principles of echography and its technique are briefly explanded, and 8 personal cases examined for suspected aneurysm of the abdominal aorta are presented. Correct and accurate diagnosis was obtained in cases. In 1 case, aortography was also performed, though its findings were less clear. It is felt that the applications of echography can usefully be extended to the screening, diagnosis and control of this form.

Aorta, Abdominal

[Echographic possibilities in surgical lesions of infancy].

The possibilities of applying ultrasound diagnosis techniques to the morphological and structural study of the soft tissues in infant surgical pathology have been examined. The technique's objective features mean that it is reliable in between 98 and 100% of cases of solid and cystic lesion identification and differentiation. In the further differentiation of solid lesions, such diagnostic accuracy may be limited by the operator's subjective experience and, objectively, by the dimensions of the lesions. Possibilities for application include thyroid, thoracic and abdominal pathology in preoperative diagnosis, postoperative control and in the monitoring of antineoplastic chemo- and radiotherapy. The peculiar features of the technique, i.e. its harmlessness and thus easy repeatibility, atraumaticity, and time and cost economy, are considered and it is concluded that it can be usefully employed on an extensive basis in the various field of infant surgical pathology, in view of the fact that other investigations always present some degree of risk and danger.

Abdomen

[Echography in the diagnosis of kidney diseases].

Nephrosonography has become a useful diagnostic tool in assessing renal disease. Parenchymal structure can be viewed by stable B-scan or A-scan and, even better, on the grey scale. The principles of applying ultrasounds and for examining results are described together with percutaneous renal punction and nephrostomy guided by ultrasounds. Current applications of echography in congenital and adult diseases are outlined and it is pointed out that the method is simple, non-invasive and precise in differentiating solid from cystic lesions, for appraising solid structures and establishing whether a mass is renal or extrarenal. Experience obtained in evaluating renal lesions and the most typical pictures of these lesions are presented. It is concluded that nephrosonography, independently of renal function, is an excellent method for investigating the kidney, has numerous advantages and is free from danger.

Age Factors

[Cytologic diagnosis of stomach neoplasms].

Personal experience in the cytological diagnosis of gastric neoplasis acquired in a series of 104 patients is presented. Three false positives were detected in 29 cases of supposed malignancy and 11 false negatives in 75 patients with tumours thought to be benign. Cytology often proved the determining factor in the planning of surgery, while in some instances it also gave an indication of the histological type involved.

Adenocarcinoma

[Ultrasonic diagnosis of aneurysms of the abdominal aorta].

The principles of ultrasound diagnosis are briefly explained and the technique of the examination is described with particular reference to the measures taken to ensure the exact measurement of diameters. The modalities for the echographic presentation of the normal and aneurysmatic aorta is illustrated, together with the respective pictures. It is suggested that echography be employed both as a preliminary technique and as a supplement to angiography, which is not itself particularly applicable in the case of aneurysms. Above all, it can be considered as the sole and resolutive examination on account of the findings it offers.

Angiography