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Biomedical subjects

E E Harrison

Publications and source records attributed to E E Harrison.

29 records · Page 2Linked to original sources

Method of managing the small aortic annulus during valve replacement.

In a series of 130 patients undergoing aortic valve replacement, 20 had the ascending aorta enlarged with a Dacron patch. Eight of these required division of the annulus with extension of the incision inferiorly to the anterior leaflet of the mitral valve. The resulting separation of the annulus allowed a larger size valve to be inserted. Glutaraldehyde-fixed procine heterografts were used in all patients having the annulus enlarged. No deaths occurred in those patients having annular enlargement, and the post-operative studies show no evidence of mitral valve dysfunction.

Adolescent↗

Sudden cardiac death: a retrospective and prospective study.

Since the inception of mobile coronary care units (MCCU), patients with sudden cardiac death (SCD) saved by advanced emergency medical technicians (EMT-A) can be studied retrospectively and prospectively. Forty-eight cases of SCD found in ventricular fibrillation (VF) were successfully resuscitated. Only 32% had a myocardial infarction. Most survivors were New York Heart Association (NYHA) class I or II. All class IV survivors with severe congestive heart failure died within 45 days. All class II survivors had angina as the limiting factor. Of all patients with VF, 23% survived. Eighty percent of survivors were class I or II and have resumed previous lifestyles. No clear cut symptom complex was identified. Rescue response time was generally less than five minutes. Intracardiac medications were administered without complications. Empirical administration of sodium bicarbonate correlated poorly with arterial blood gas determinations.

Administration, Topical↗

Hemolytic anemia and thrombocytopenia associated with penicillamine ingestion.

A case of a 52-year-old white woman who developed hemolytic anemia and thrombocytopenia after receiving D-penicillamine is presented. Although there appears to be a causative relationship, it cannot be documented at this time. No other case of hemolysis has been suggested in patients treated with penicillamine. Since penicillamine is being used more frequently and in an ever-growing list of conditions, it is advisable to be alert to the possibility of hemolytic anemia as another of the complications of therapy.

Anemia, Hemolytic↗

Effects of age and gender on the relationship between anxiety and coronary artery disease.

This study investigated the relationship between anxiety and coronary artery disease (CAD). State (S-ANX) and trait (T-ANX) anxiety were assessed with the State-Trait Personality Inventory (STPI), which was administered to 373 patients (230 males, 143 females) 12 to 18 hr prior to their undergoing coronary arteriography. Females were significantly higher than males in both T-ANX (p less than 0.05) and S-ANX (p less than 0.01). Younger patients of both sexes were significantly higher in S-ANX (p less than 0.001), but no relationship was found between T-ANX and age. Patients with CAD did not differ in S-ANX from those without CAD. T-ANX scores of female patients were unrelated to MI or CAD. Male patients with chest pain only (CPO) were higher in T-ANX than males with prior myocardial infarction or chest pain plus CAD (p less than 0.01). Although this difference was not significant for older males (p less than 0.31), younger CPO males were significantly higher in T-ANX than the other clinical groups (p less than 0.05). These results were interpreted as indicating that high T-ANX is not associated with CAD, but is a risk factor for angiography, especially for younger males.

Adult↗