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E E Shuĭkina

Publications and source records attributed to E E Shuĭkina.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The comparative characteristics of the clinico-immunological indices in different contingents of opisthorchiasis patients in a hyperendemic focus. 4. The transplacental transmission of Opisthorchis felineus antigens].

25 women in labour with chronic opisthorchiasis have been examined. They were representatives of native (7), local (8) and migrated population of the focus. Control group comprised 10 women from the local population free of invasion. Their immune status was assessed by the level of IgA, IgG, IgM, circulating immune complexes (CIC) and specific antibodies in the serum obtained from peripheral and funic veins, as determined by enzyme immunoassay (ELISA). To detect opisthorchis antigens in the serum modified radial immunodiffusion test was used. Antibody titres in ELISA, IgG and CIC levels were the highest in migrated women. Antibody titres in ELISA and IgG level in the newborn of migrated women were also considerably higher than in other newborn. Serum IgM level in all groups of newborn was considerably lower than in their mothers and IgA was altogether undetectable. In 3 native and 2 local women the results of immunodiffusion test were positive. It is suggested that transplacental migration of opisthorchis throughout the neonatal period may lead to tolerance formation.

Adult↗
PubMedDate not supplied

[Clinical and epidemiologic immunology aspects of parasitic diseases].

Principal trends in clinical immunological studies applied to the clinical picture and epidemiology of parasitic diseases are outlined. The author presents definitions of clinical and epidemiological immunology, describes their interrelation, gives reasons for false positive results from immunoepidemiological, mainly, serological observations.

Humans↗