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Biomedical subjects

E Eck

Publications and source records attributed to E Eck.

6 recordsLinked to original sources
PubMed1978

In vitro effects of inosine-pyruvate-phosphate on P50 values and DPG contents of fresh and stored blood from healthy neonates, symptom-free premature infants and premature infants with respiratory distress syndrome.

A study was made of the effect of a 3-hour incubation with inosine-pyruvate-phosphate (IPP) on the P50 values and 2,3-DPG contents of fresh blood and blood which had stood for 96 h, from healthy adults, term neonates, 1-2-week-old symptom-free premature infants and RDS premature infants. It was found that the P50 value and the 2,3-DPG content could be increased considerably by IPP treatment in both the fresh and the stood blood in the various groups of neonates. The question remains open as to whether the effect of IPP, in significantly improving the O2 transport in neonates, is a consequence of the 2,3-DPG alone or of some other metabolite. In RDS the stimulating effect of the IPP mixture is appreciably lower.

Adult↗
PubMed1977

Favourable effect of storage at 0 degrees C on the O2 transport function of heparinized blood.

The biological value of heparinized blood was found to decrease less on storage at 0 degrees C than on storage at +4 degrees C. At 0 degrees C the P50 value decreases substantially later and less, the blood is less acidotic, and the UV absorption of the dialysate is less enhanced than at +4 degrees C. The findings justify a further search for the conditions suitable for the widespread practical application of storage at 0 degrees C.

Biological Transport↗
PubMed1977

[Ultraviolet spectrophotomerty studies of serum dialysate from patients with long term intermittent artificial kidney treatment].

In 16 chronically dialysed uraemic patients in the course of altogether 61 treatments with the artificial kidney the UV-absorption spectre of the in-vitro-dialysate of the serum was studied. In uraemia on account of the retention of the metabolic products the UV-absorption spectre of the serum dialysate is extremely increased, a decrease is to be registered after the dialysis. The method discussed is suitable for the control of the effectiveness of haemodialysis and gives a more complex picture concerning the changes during the treatment than the usual laboratory parameters.

Blood Urea Nitrogen↗
PubMed1977

[Experiences with the hyperoxia test in neonates and infants with congenital heart malformations (author's transl)].

Hyperoxia test with arterialized capillary blood was performed in 63 neonates and infants suffering from congenital heart defect with shunt. The lowest values were found in neonates with transposition of the great arteries without major systemic-pulmonary shunt. In cases with left to right shunt requiring surgical intervention the pO2 increased less than in those not needing operation. Observations with this non-invasive mentod proved valuable in early recogniton of congenital heart defect of neonates and infants requiring urgent surgical treatment.

Arteries↗
PubMed1976

Experiments on placental circulation and transplacental transfer in exteriorized foetuses in hypoxia and after asphyxia in guinea pigs.

Experiments were carried out on near term pregnant guinea pigs. Cesarean section was performed and by exteriorization of the foetuses the placental stage of labor was simulated. In one group of foetuses, chosen at random, we induced hypoxia, and in an another series of experiments asphyxia, each group with its own control. The results of acid-base values, experimental antipyrine transplacental transfer studies and the survival rate of foetuses, showed that it is advantageous for the newborn animal if we preserve the placental function in such conditions immediately post partum. Further study is necessary to determine to what degree and under what conditions our experimental observations are applicable to human perinatology.

Animals↗