Intralesional interferon therapy for basal cell carcinoma.
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Biomedical subjects
Publications and source records attributed to E Epstein.
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Patient instruction sheets are a patient pleasing practice tool, especially if used creatively before seeing patients, to augment telephone conversations, and to detail postoperative care. Customizing, availability, and other strategies for optimal use of patient instruction sheets are discussed. Although patient instruction sheets are significant time savers, their updating, customizing, and effective use requires a small investment of physician time and effort.
Accidental intravascular injection of lidocaine during the induction of infiltration anesthesia for dermatologic surgery is an occasional and harmless occurrence. The author noted nine such episodes in a three-year period of full-time private dermatologic practice. A very brief, sharp, stinging pain lasting only seconds and immediately followed by blanching in a vascular distribution characterized these episodes. The blanching, resulting from the 1:200,000 epinephrine solution used in the lidocaine solution usually disappeared within five to ten minutes. Patients experienced no ill effects. The standard textbooks and reviews caution practitioners to aspirate before injecting a local anesthetic; this is unnecessary when performing infiltration anesthesia of the skin.
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Excision of primary malignant melanomas by a cautery (actual heat) or by endothermy (electric cutting current) is a simple method of management. It consists of excision of a disc of tissue that contains the evident malignancy plus some surrounding normal-appearing skin.
In all probability, a patient with a primary malignant melanoma, but without clinical, radiological or other laboratory evidence of metastases, has a 75 to 80% chance of living five years and 55 to 65% of surviving for ten years regardless of other prognostic factors and the skill with which surgical therapy is applied. It has not been established whether or not malignant melanomas are absolutely curable.
The buried horizontal mattress suture (BHMS) is a new tension suture technique using synthetic absorbable polyglactin 910 suture. When used in minor surgery of the trunk and extremities, this technique eliminates significant suture marking.
Digital mucous cysts can be effectively managed by multiple needlings and expression of contents. This simple technique cures about two thirds of the lesions. Most of those remaining are reduced to small asymptomatic nodules.
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