PubMed Health⌕ Search

Biomedical subjects

E F Chernushenko

Publications and source records attributed to E F Chernushenko.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Effect of leukocytic interferon on the functional state of bronchoalveolar phagocytes in lung diseases].

A study was made of the effect of leukocytic interferon on the phagocytic activity of alveolar macrophages and neutrophils in patients with chronic bronchitis, tuberculosis and sarcoidosis of the lungs. Cells isolated from the patients' bronchoalveolar washing off were used. It was concluded that short-term incubation of macrophages and neutrophils with interferon resulted in phagocytosis enhancement and increased intensity of metabolic processes in them. Interferon produced the most noticeable effect on cells with an initially reduced absorption capacity.

Adjuvants, Immunologic↗
PubMed1984

[Determination of alveolar macrophage function in nonspecific lung diseases by the simultaneous estimation of phagocytosis and acid phosphatase activity].

The aim of this investigation was to increase the accuracy of the determination of the functional activity of alveolar macrophages with phagocytic functions, isolated from bronchial washings, to reduce the time necessary for this determination and to compare the results thus obtained with the clinical signs of the disease. 46 patients with nonspecific pulmonary diseases were examined. The method of the simultaneous evaluation of the phagocytic activity of alveolar macrophages and the level of acidic phosphatase activity during phagocytosis was found to ensure greater accuracy in the determination of the functional activity of alveolar macrophages and to reduce the time necessary for the evaluation of the reaction by 1.5 hours. In patients with non-specific pulmonary diseases the phagocytic activity of alveolar macrophages decreased, which was accompanied by a lower level of acidic phosphatase consumption.

Acid Phosphatase↗
PubMed1983

[Effect of experimental cefuroxime on the immunologic reactivity of the body].

The effect of ketocef or cefuroxim, a new cephalosporin antibiotic, on the immune system was studied on mice. The repeated use of the drug for 10 days a dose of 30 mg/kg injected intramuscularly did not result in suppression of the immune status. The number of the rosette forming cells of the thymus and spleen did not change. The production of hemolysin as shown by the number of the antibody forming cells somewhat increased, when the animals were immunized with the sheep red blood cells. A certain decrease in the intensity of the anaphylactic reaction was observed in sensitization of the animals with bovine serum.

Anaphylaxis↗