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Biomedical subjects

E F Chernushenko

Publications and source records attributed to E F Chernushenko.

69 records · Page 4Linked to original sources

[The immunological and cytogenetic changes in patients with pulmonary tuberculosis].

The performed studies showed that patients with active phase pulmonary tuberculosis have their T-system function suppressed, that of B-system activated, this phenomenon being the most marked in those patients with fibrocavernous tuberculosis. Increase in the activity of phagocytes was more common in patients with infiltrative tuberculosis. The immunity system state in subjects with non-active post tuberculous alterations did not depart from normal values. DNA and RNA concentrations were decreased in those patients having more pronounced immunologic disturbances (infiltrative and fibrocavernous tuberculosis), reparative capacity of RNA being altered only in patients with focal tuberculosis. Strong correlation was established between immunologic and cytogenetic indices.

B-Lymphocytes↗

[The characteristics of the immune status of patients with chronic obstructive bronchitis in PiM phenotypic variants of the alpha 1-proteinase inhibitor].

The connection between alpha 1-proteinase inhibitor variants and immunity disorders in patients with chronic obstructive bronchitis is considered in the article. As a result of investigation disorders of both T- and B-immunity systems were found. They consisted in decrease of the content and proliferative activity of T-lymphocytes, changes in their populational composition, dysfunction of B-lymphocytes, dysimmunoglobulinemia. These changes were more pronounced in allele M3+ carriers constituting the risk group on chronic lung diseases.

Adult↗