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Biomedical subjects

E F Gherlone

Publications and source records attributed to E F Gherlone.

At least 19 recordsLinked to original sources

Orientation of craniofacial planes and temporomandibular disorder in young adults with normal occlusion.

The aim of this study was to investigate the relationship between orientation of craniofacial planes relative to the true horizontal and temporomandibular disorder (TMD), in normal occlusion. Fourteen university dental students, with full natural dentition and bilateral Angle Class I occlusion, who exhibited signs and symptoms of TMD, were compared with 14 age- and sex-matched healthy controls. Frontal and lateral photographs were taken in natural head position with the subject standing up, clenching a Fox plane and having a facial arch positioned. Photographs were examined by a standardized image analysis. Inter-pupillary axis, Frankfurt, occlusal and Camper planes were evaluated. In frontal view, the Frankfurt plane was right rotated relative to the true horizontal both in TMD subjects (P < 0.01) and controls (P < 0.05), but rotation was larger in TMD subjects (mean difference between groups, 1.1 degrees, 95% confidence interval, 95% CI, 0.2-2.0 degrees ). No significant deviation from the horizontal or difference between groups was observed for the interpupillary axis and occlusal plane. In lateral view, the Frankfurt plane was upward-orientated relative to the true horizontal in TMD group (mean angular deviation 2.8 degrees, 95% CI, 1.0-4.6 degrees ). The occlusal and Camper planes were downward-orientated in both groups (P < 0.0001), but inclination of occlusal plane tended to be smaller in TMD subjects (mean difference between groups, -3.8 degrees, 95% CI, -7.6-0.1 degrees ). Angles between any craniofacial planes did not significantly differ between groups. The findings show that in young adults with normal occlusion, a weak association exists between the orientation of craniofacial planes in natural head position and signs and symptoms of TMD. Furthermore, they suggest that, within this population, TMD might be mainly associated with head posture rather than with craniofacial morphology.

Adult↗

The distribution of occlusal contacts in the intercuspal position and temporomandibular disorder.

The aim of this study was to describe the distribution of occlusal contacts in subjects with signs or symptoms of temporomandibular disorder (TMD), and to assess whether any difference exists with healthy subjects. Twenty-five university dental students with complete natural dentition who exhibited TMD (13 females and 12 males, age from 19 to 30 years) and 25 age- and sex-matched controls entered the study. Occlusal contacts were evaluated in the intercuspal position and wax registrations were made in all subjects. Occlusal contacts were classified according to location and intensity. No differences were found between TMD and control groups for the overall number and distribution of contacts or for any side and intensity of contact. An intra-subject analysis showed that TMD subjects had significantly greater bilateral asymmetry in the number of contacts than controls. Median absolute difference of the number of contacts on right and left sides was 3 (95% CI, 2-4) in TMD subjects and 2 (95% CI, 1-2) in controls. In TMD subjects with mono-lateral TMD there was a significant concordance (88.9%) between the side of disorder and the side of higher number of contacts. These findings, while confirming that a significant relationship exists between distribution of occlusal contacts and TMD, further suggest that in young adults it may be primarily expressed by asymmetries in occlusal contact patterns. Existence and aetiology of any association of TMD with occlusal contacts should be further investigated.

Adult↗

The relationship of bruxism with craniofacial pain and symptoms from the masticatory system in the adult population.

The association of bruxism with craniofacial pain and symptoms of dysfunction of the masticatory system was assessed in a sample of 483 adult subjects, aged 18-75 years and selected from the general population living in the municipality of Segrate, a metropolitan area in northern Italy. Subjects were interviewed by a questionnaire about oral conditions, occurrence of symptoms of masticatory disturbances, craniofacial and neck pain. The overall prevalence of bruxism was 31;4% (95% confidence interval (CI): 27;3-35;5%). At univariate analysis bruxism was significantly associated with craniofacial pain, difficulty in closing the mouth, difficulty in opening the mouth wide or in locking the mouth, temporomandibular joint sounds, pain on movement, a feeling of stiffness or fatigue of the jaws, and neck pain. After adjustment for reciprocal influences and confounding variables, logistic regression analysis disclosed a strong independent association of bruxism with difficulty in closing the mouth (adjusted odds ratio, (OR): 2;84, 95% CI: 1;68-4;48), and a weaker relationship with craniofacial pain (adjusted OR: 1;84, 95% CI: 1;16-2;93) and temporomandibular joint sounds (adjusted OR: 1;64, 95% CI: 1;00-2;69). The findings show that in the general adult population there is a complex connection among bruxism, craniofacial pain and symptoms of masticatory disturbances. Furthermore, they suggest that the most direct relationship of bruxism may be with difficulties in mouth movements, but also an independent association may exist with craniofacial pain and other symptoms of temporomandibular disorder.

Adult↗

Association between loss of occlusal support and symptoms of functional disturbances of the masticatory system.

The purpose of this study was to evaluate the association of loss of occlusal support with symptoms of functional disturbances of the masticatory system, in particular with the ones related to the temporomandibular dysfunction. A total of 483 adult subjects randomly selected from the population living in the municipality of Segrate, northern Italy, were studied. Subjects were interviewed by questionnaire about oral conditions and occurrence of symptoms of disturbances of the masticatory system. Also, denture was examined by dentists during the interview. Loss of occlusal support was observed in 60.2% of the subjects, symptoms of functional disturbances in 68.7% and temporomandibular dysfunction in 55.1%. At univariate analysis loss of occlusal support was mainly associated with a feeling of stiffness or fatigue of the jaws (P < 0.001), difficulty in closing the mouth (P < 0.005) and difficulty on mastication (P < 0.0001). Association with temporomandibular dysfunction as a whole was significant also (P < 0.001). Multiple age- and sex-adjusted logistic analysis disclosed a significant strong impact of loss of occlusal support on difficulty with mastication (odds ratio = 7.0, P < 0.0001). At that analysis, no significant relationship resulted with symptoms of temporomandibular dysfunction. These findings confirm that presence of an adequate occlusal support is a relevant factor in maintaining an efficient chewing, and also suggest that it may play any indirect role in preventing occurrence of symptoms of temporomandibular dysfunction.

Adolescent↗

[Cephroxadine--a new antibiotic. Clinical experience].

Cephroxadine is an orally active cephalosporin of third generation. The most important characteristics are: 1) bacterial cell wall synthesis inhibition during active multiplication; 2) wide spectrum of action, including Gram+ and Gram- bacteria and also penicillinase and beta-lactamase producers; 3) possibility of oral administration, quick assimilation and daily moderate dosage (500 mg/12 h). This antibiotic was tested on 71 patients to prevent and resolve dental pre-and post-operating infections. In all tested cases Cephroxadine was very effective and resolved well symptoms on second day, generally. Moreover no patient had any collateral effect to justify interruption of therapy.

Adolescent↗

[Magnetic attachments for implants in complete dentures].

In this research work we examine and apply to patients new types of technologies, describing advantages and disadvantages of using them. This osseointegrated implantation with magnetic prosthetic connection, allow to stabilize complete denture in patients suffering from serious atrophy.

Dental Implantation, Endosseous↗