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Biomedical subjects

E F Gocka

Publications and source records attributed to E F Gocka.

14 recordsLinked to original sources
PubMed1989

Audiometric configuration as a reflection of low plasma glucose and diabetes.

Forty-five subjects with a rising, progressively improving (RPI) audiometric pattern were considered for a 5-hour oral-glucose tolerance test. Results revealed that 2 nondiabetic subjects (4%) had a plasma glucose nadir of 49 mg/dl or lower and 7 nondiabetic subjects had a nadir between 50 and 57 mg/dl. A total of 21% of 42 subjects with data indicated abnormally low readings. An additional 7 subjects were found to be diabetic; 5 subjects had impaired glucose tolerance, and 9 other subjects had nondiagnostic glucose intolerance, totalling 47% of 45 subjects in the study with abnormally elevated plasma glucose levels. Therefore a total of approximately 68% of all subjects in our study indicated metabolic dysfunction based specifically on a RPI pattern.

Adult↗
PubMed1988

Audiometric configuration as a reflection of diabetes.

The purpose of this study was to investigate whether or not a rising, progressively improving (RPI) sensorineural hearing loss from lower toward higher frequencies might be related to or serve as an indicator or predictor of diabetes. Forty-five subjects between the ages of 21 and 79, demonstrating a RPI audiometric pattern, were considered for a 5-hour oral glucose tolerance test. Based on the National Diabetes Data Group standard, results showed that diabetes mellitus appeared in seven subjects; five subjects had impaired glucose tolerance; and nine subjects had mild but nondiagnostic glucose intolerance. Relatively normal glucose values were demonstrated by 53% of subjects. There may be some value in an RPI audiometric pattern as an indicator or early detection sign for diabetes, but further research is necessary before such conclusions can be drawn.

Adult↗
PubMed1986

Self-ratings of typical mood and behavior during recovery from alcohol abuse. A multivariate study of alcoholic men.

Male alcoholic subjects were asked to rate their own typical dysphoric mood states soon after admission for alcohol detoxification and again following 2 weeks of recovery from alcohol abuse. Self-ratings of typical dysphoric mood decreased following 2 weeks of recovery from alcohol abuse while self-ratings of typical impulsive behaviors remained unchanged. Within subjects, the magnitude of change in ratings of typical dysphoric mood during the first 2 weeks of recovery from alcohol abuse correlated highly with the level of typical dysphoric mood measured at the onset of alcohol treatment.

Adult↗
PubMed1980

An interactive computer program that accurately estimates the ED50, its standard error and other parameters related to the probit regression line.

A program suitable for terminal, conversational-mode usage was developed in the BASIC language to compute the median effective dose (LD50), various error terms, and confidence intervals. The overall algorithm used in the program was based on a method described by Finney. The accuracy, speed and flexibility of the program makes the terminal approach an efficient alternative to simple graphic methods.

Computers↗
PubMed1977

A method of fitting non-symmetric Gompertz functions for characterising malignant growth.

A basic symmetrically asymptotic Gompertz equation was extended to account for more complex growth and life-table data. This extended Gompertz or non-symmetric asymptotic regression equation was found to be suitable for fitting a large variety of data exhibiting growth and experimentally-induced regression effects expressed in the same curve. The statistical and computational properties of this fitting function are discussed in theory and example.

Animals↗