[Morphological changes and metabolic disorders in the heart muscle in local and whole-body experimental irradiation].
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Biomedical subjects
Publications and source records attributed to E F Lushnikov.
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Thyroid carcinoma is a documented medical consequence of the Chernobyl accident, but medicobiological and other aspects of this problem are not yet understood completely because Chernobyl thyroid carcinoma (CTC) is not a single nosological entity but an integrated notion including various groups of population of different age and sex, pollution of the territory, various histogenesis (A-, C-cells) and morphogenesis, latent period (minimal 4 years, maximal not yet known), variable clinical and morphological manifestations. Further CTC studies are needed on a special long-term program.
Presented are the results of morphological studies of radiation sickness, congenital malformations and malignant tumors which have developed in Chemobyl victims. Until now consequences of the accident remain a subject of practical and research medicine. Scope of relevant topical problems the pathologists will have to investigate in the future is discussed.
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Medico-biological sequelae of irradiation of humans as a result of the Chernobyl accident are considered. Acute radiation sickness, thyroid carcinoma in children, chromosomal aberrations in the peripheral blood lymphocytes have an etiological link with radiation. Three problems are important for future studies: 1) collection of reliable information about the radiation, 2) assessment of dose-effect relations, 3) organization of supervision.
There is an increase of thyroid carcinoma incidence in regions contaminated after the Chernobyl accident as well as in Russia on the whole. The most considerable increase occurred in younger age groups of population. No difference in thyroid tumors structure was found in polluted with radionuclides and non-polluted regions.