[The complications of diphtheria].
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Acute Disease↗
Biomedical subjects
E F Sedak
Publications and source records attributed to E F Sedak.
[Initial experience with bronchoscopy in diphtheria].
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Adolescent↗
[Genetic characterisation of wild measles strains circulating in European part of Russia in 1998-2002].
The primary structure of the N-gene COOH terminus of measles virus isolated, 1998-2000, in Russia's European part was investigated. The general analysis as well as an analysis of the primary gene structure showed the two group's isolates as belonging to the D4 genotype. A subsequent analysis of the primary structure of the N-gene COOH-terminus of Moscow/2002/61 isolated during the 2002 measles outbreak in Moscow also showed it as belonging to the D4 genotype. The obtained data are indicative of that the wild measles strains belonging to the D4 genotype have been recently circulating in Russia's territory.
Base Sequence↗
[The local manifestations of diphtheria].
The development of diphtheria is characterized by a pronounced local process, but the description of local changes in the disease are based only on postmortem findings. 67 patients with different forms of diphtheria were examined. In 11 cases of descending croup bronchoscopic examination was carried out. As revealed in this study, at the primary stage of the disease films cover the whole of the air duct system, and the process is identical to that on tonsils. In the course of convalescence and under the action of specific antiserum films on the tonsils, the soft palate and the vocal cords disappeared, and films in the larynx, the trachea and bronchi could be easily separated from the mucous membrane, but always with the formation of erosions and even perforations in it. The character of the process was indicative of the absence of any specific action of diphtheria toxin on the mucous membrane at the site of the inoculation of the infective agent. No correlation between the severity of the course of diphtheria, the degree of edema and the frequency of the development of complications was noted.
Adolescent↗