PubMed Health⌕ Search

Biomedical subjects

E Fabian

Publications and source records attributed to E Fabian.

At least 19 recordsLinked to original sources
PubMed2006

[Principals and clinical applications of optical coherence tomography in glaucoma].

Optical coherence tomography (OCT) supplies morphological information from different retinal layers. In glaucoma, analysis of the nerve fiber layer is gaining more and more significance: Losses in this layer often precede by years functional losses in the visual field and end up in optical nerve head changes. OCT offers a means for imaging and for measurement of the nerve fiber layer besides morphological analysis of ONH as one of the earliest sensitive parameters in modern glaucoma diagnostics. However, because of the lack of extensive comparative data, the priority use of optical coherence morphometry is to be seen mainly in intraindividual follow-up.

Glaucoma↗
PubMed2001

Ethical considerations on dynamic psychiatry and the tradition of relationship in psychoanalysis. An historical overview.

The historical tradition of psychoanalysis as the therapeutic science of interpersonal processes is traced back to its roots in Freud and discussed in its therapeutic and philosophical implications. The Berlin School of Dynamic Psychiatry enlarges the interpersonal principle with the therapeutic concept of group dynamics, identity and of social energy, giving it an implication of therapeutic optimism and a new ethical significance.

Ethics, Medical↗
PubMed1998

[Teleconsultation network for ophthalmology--experiences and results].

MOTIVATION: Telemedical services for ophthalmology are developed within the OPHTEL project, which has been funded by the European Union and by the Bavarian government in the Bavaria-online initiative. METHODS: Seven private ophthalmologists, one university eye clinic, one clinical Diabetes center and an informatics research institute are connected within a teleconsultation network. Asynchronous (based on Internet E-Mail) and synchronous (based on ISDN-mediated videoconferencing tools) types of teleconsultations are realized. RESULTS: 86 teleconsultations (62 asynchronous, 23 synchronous) took place within the first 10 months. Complex and rare eye diseases as well as interdisciplinary questions (ophthalmology--diabetology) are the main area of medical communication interest. Legal and security problems are discussed. CONCLUSIONS: Telemedical services must be understood as a complete process of medical care on the basis of modern communication technologies, which influences also the management of this process.

Computer Communication Networks↗
PubMed1995

Effect of testicular damage induced by cryptorchidism on insulin-like growth factor I receptors in rat Sertoli cells.

The distribution and density of functional insulin-like growth factor I (IGF-I) receptors in cryptorchid and scrotal rat testes and epididymides during gonadal development were studied. Cryptorchidism was induced by unilateral gubernaculectomy in 4-day-old animals, and organs were studied at 15, 30, 60 and 90 days of age. Tissue membranes were assayed for 125I-labelled IGF-I binding. Characterization and specificity of binding sites showed that both normal and contralateral undescended testes and epididymides exhibited typical type 1 IGF receptors. In normal testes, IGF-I receptor density was 20.6 nmol g-1 wet mass at day 15, and decreased to 12.8 nmol g-1 wet mass at adult age (day 90). Cryptorchid testes showed IGF-I receptor concentrations similar to normal testes at day 15 and day 30, but in postpubertal stages displayed a divergent pattern, with a continuous increase at day 60 and day 90, reaching a higher density than those found for immature ages (62 nmol g-1 wet mass). Both normal and cryptorchid epididymides had a similar concentration and a comparable decrease in IGF-I receptors throughout development. In studies with immunohistochemical techniques (alpha IR-3 antibody), IGF-I receptors were found in primary spermatocytes, Sertoli cells and Leydig cells. Cryptorchid tubules showed a lack of germinal epithelium and a marked increase of immunoreactive IGF-I receptors in Sertoli cells, compared with normal tubules from scrotal testes. Intense immunoreactivity for IGF-I receptors was present in the principal cells of epididymal tubules in both normal and cryptorchid organs.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1991

Spinal anesthesia reduces the hazard of apnea in high-risk infants.

General anesthesia in premature babies is associated with a significant risk of life-threatening apnea. Spinal anesthesia in the high-risk infant is simple, safe, and effective, but the incidence of apnea with its use has not been previously determined. The total absence of apnea in 84 high-risk infants suggests that surgery below the umbilicus under spinal anesthesia can safely be performed on an outpatient basis in preterm infants or babies with a history of apnea. Ketamine as an adjunctive agent adds no apparent risk. The technique is relatively easy, surgery is not compromised, and parental acceptance is high.

Anesthesia, General↗
PubMed1990

[A new laser scan system for video ophthalmoscopy. Initial clinical experiences also in relation to digital image processing].

The clinical advantages of a scanning laser ophthalmoscope (SLO) and video imaging of fundus pictures are described. Image quality (contrast, depth of field) and imaging possibilities (confocal stop) are assessed. Imaging with different lasers (argon, He-Ne) and changes in imaging rendered possible by confocal alignment of the imaging optics are discussed. Hard copies from video images are still of inferior quality compared to fundus photographs. Methods of direct processing and retrieval of digitally stored SLO video fundus images are illustrated by examples. Modifications for a definitive laser scanning system - in regard to the field of view and the quality of hard copies - are proposed.

Computer Systems↗
PubMed1987

Interphasic nucleolus organizer regions visualized by silver reaction in human hepatocytes.

To provide more information on the presence and number of nucleolar silver-stained granules (SSGs) representing interphasic nucleolus organizer regions (NORs) responsible for ribosomal RNA synthesis, these cells were studied in patients with various hepatic disorders such as chronic hepatitis and liver cirrhosis with or without characteristic signs of progress of the disease ("active" and "inactive" cirrhosis). In comparison with hepatocytes of histologically normal liver, an elevated number of nucleolar SSGs were noted in hepatocytes of patients with all the mentioned hepatic disorders, with maximal values in patients with "active" liver cirrhosis. These findings suggest a compensatory nucleolar biosynthetic activity in remaining or altered hepatocytes in studied liver disorders.

Biopsy, Needle↗
PubMed1986

[Injuries of the corneal endothelium].

Examples of "endogenous" or direct and "endogenous" or indirect endothelial trauma are presented. Corneal contusion, McCannel suture, YAG laser iridectomy, congenital luxation of the lens, and chronic over wearing of contact lenses all cause traumatic changes. The etiology and effects of these changes are discussed. Specular microscopy of the corneal endothelium permits good clinical control of both the trauma and wound healing.

Adult↗
PubMed1983

[Morphometry of the endothelium using automated television image analysis].

Report on the use of a new image processing system (IPS) for automated morphometry of the corneal endothelium. The method is demonstrated with endothelial photographs taken with the aid of a Keeler-Konan wide angle specular microscope. The original picture is enlarged ten times, then digitized, detected, and analyzed. Areas containing 100-250 endothelial cells can be evaluated automatically. Depending on the quality of the photographs, larger areas sometimes require interaction by the investigator. The evaluation of a 621-cell picture is demonstrated step by step. The time saving which the method offers and its objectivity are discussed, as well as its use in combination with different specular microscopes.

Cell Count↗
PubMed1980

[Bilateral occlusion of the internal carotid artery with binasal visual field defect and partial optic atrophy (author's transl)].

A case of bilateral thrombotic occlusion of the internal carotid arteries is reported, with binasal quasiquadrant hemianopsia and partial optic atrophy as the only symptoms. Based on a survey of the literature on internal carotid occclusions and their collateral anastomoses, as well as on their ophthalmologic signs, the possible pathogenetic mechanisms are discussed.

Carotid Artery Thrombosis↗
PubMed1977

Lipoprotein lipase and postheparin esterase activity in primary hyperlipoproteinaemia type IV and V.

In a study of the aetiopathogenesis of primary hyperlipoproteinaemias, which has not yet been elucidated, we paid attention to the heparin-activated lipolytic enzymes. Lipoprotein lipase (LPL) and postheparin esterase (PHE) activity was determined in 35 patients with primary hyperlipoproteinaemia (HLP) type IV (average age 50 years), 28 with type V (average age 48 years) and 2 with type III (57 and 62 years). Since PHE activity is correlated to sex and in women also to age, these factors had to be taken into account. The average activity values for the given enzymes in the patients group did not differ from the results in the control group. From these enzymes activities we tried to analyse the findings in individual cases in which the values were lower or higher than the control group range. The low PHE activity in some patients with type IV and V was evidently secondary and due to hepatobiliary disorder (most frequently liver steatosis). The simultaneous elevation of LPL and PHE activity in type IV and V patients with a high serum lipoprotein concentration shows that the response of patients with extreme HLP to heparin is more pronounced. The low PHE activity in type III (tested in only 2 patients) could possibly indicate the liver disorder on which this metabolic disease may be based.

Clinical Enzyme Tests↗