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Biomedical subjects

E Fedor

Publications and source records attributed to E Fedor.

13 recordsLinked to original sources

The role of ischaemia in the formation of postoperative intra-abdominal adhesions.

The formation of intra-abdominal adhesions was studied in animal experiments. In dogs, the peritoneal lining was eliminated on the left side of the abdominal wall, while ischaemia was elicited contralaterally by suturing the main vessels. Two to seven weeks later no omental adhesion could be found on the abdominal wall deprived of peritoneum, while it developed in 11 of the 13 operated animals in the ischaemic area.

Abdominal Muscles↗

[Comparative studies of plication surgery under experimental conditions].

Adhesions of the small intestine were produced by scarification in 43 dogs. The 38 surviving animals were relaparotomised after 3 weeks and the adhesions were separated. Afterwards the Noble operation in 11 animals, the modified operation by Childs in 10 animals, the interior splinting of the small intestine by Reifferscheid-Phillipp in 10 animals, and the simple closure of the abdominal cavity in 7 animals (control group) were carried out. The autopsy was performed 1 to 8 weeks after the operation. The intestine was in perfect plication order after the noble operation. Overlapping of loops without complications were existing after the operation by Childs. Unsystematic fixations without kinking were observed after the interior splinting, but in one case no adhesion was visible after 2 months and in another case a heavy inflammation of the abdominal wall was caused by the splint. Kinking, unsystematic fixation, and wide lumina without ileus were discovered in the control group. - The Noble operation is expanding with reference to the time. The operation by Childs is a simple and short-term operation. The interior splinting under experimental circumstances is a lengthy and traumatising procedure in the opinion of the author.

Animals↗

[Experimental studies of circulation following a plication operation].

Three types of plications were performed on dogs: 1. modified mesenterial plication; 2. transjejunal internal splinting; 3. intestine duplication according to Noble. No passage disorder or abnormal circulation were observed; compared with the values of the control dogs isotope activity was the same after plication. Thus, there is no danger of impaired circulation after this type of operation.

Animals↗