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E Fiorini

Publications and source records attributed to E Fiorini.

28 records · Page 2Linked to original sources
PubMed1991

[Transitory carotid ischemic attacks: clinical and pathogenic aspects].

The aim of this study is to describe the clinical characteristics and the pathological mechanisms of carotid transient ischemic attacks (TIA) in 117 patients which were hospitalised for such symptoms. Our results show a male predominance, except for age group under 40 and over 79 years. The principal cardiovascular index and risk factors are: arterial hypertension, smoking, hyperlipidemia, vascular intermittent claudication and hematocrit greater than 46%. Amongst our patients, 17% with hemispherical and mixed TIAs had a cerebral infarction proved by CT-Scan, the recent aspect and localisation of which were compatible with symptoms. The atherosclerotic causes are more frequently associated with mixed and retinal TIAs than hemispheric TIAs. This fact may be attributed to a larger proportion of stenotic atherosclerotic lesions by mixed TIAs than hemispheric ones. The cardiac embolic pathogenic mechanism is responsible for 11% of TIAs if considered individually; of 5% if associated with carotid atherosclerosis.

Adult↗
PubMedDate not supplied

[Role of platelet microaggregates in thrombocytopenia in normal and hypertensive pregnancy].

Platelet count and parameters (mean volume, MPV; volume distribution width, PDW; percent of large elements, PLCR) were examined at the third trimester, at delivery, at days 1 and 4 puerperium, in 9 primigravidae with idiopathic thrombocytopenia and 11 with pregnancy-induced hypertension (PIH) with associated thrombocytopenia, and compared with those from 27 PIH and 22 normotensive, normothrombocytemic primigravidae. All hypertensive women were treated with nifedipine alone or associated to methyldopa, clonidine or labetalol. Platelet count tends to a progressive fall during normal pregnancy, and to rough rise in puerperium, the remaining parameters being unchanged. In idiopathic thrombocytopenia the reduced count remains unchanged even in puerperium, and the increased MPV and PLCR are consistent with the presence of large, immature, circulating elements, in pregnancy as well as in puerperium. When thrombocytopenia is associated to PIH, puerperal recovery is maximum. In this case, the drop in MPV and PLCR is consistent with the resolution of microaggregates that may produce artifact in the evaluation of platelet parameters. The presence of platelet microaggregates may therefore cause overestimation of thrombocytopenia associated to PIH.

Adult↗