PubMed Health⌕ Search

Biomedical subjects

E Fitzgerald

Publications and source records attributed to E Fitzgerald.

At least 37 records · Page 2Linked to original sources
PubMed1993

Primary rhabdomyosarcoma of the diaphragm: an unusual cause of adolescent pseudo-achalasia.

We report an adolescent male who presented with progressive dysphagia. Barium examination and upper endoscopy revealed the presence of a smoothly tapered stricture at the lower end of a dilated oesophagus typical of achalasia. Further evaluation by computed tomography (CT), demonstrated the presence of a bulky infiltrating diaphragmatic mass encasing the lower oesophagus. CT guided biopsy of the mass and subsequent post mortem examination revealed the presence of a primary rhabdomyosarcoma of the diaphragm encasing the lower oesophagus. A diagnosis of pseudo-achalasia secondary to a primary diaphragmatic tumour was made.

Child↗
PubMed1992

Risk of congenital malformations associated with proximity to hazardous waste sites.

Concern about environmental pollutants has increased; however, it remains unclear whether chronic exposures to toxic chemicals in the environment occur at doses sufficient to produce adverse health effects in humans. To date, community studies have not adequately addressed this question. In this study, the authors linked two existing data bases of the New York State Department of Health to evaluate the relation between congenital malformations and residential proximity to hazardous waste sites in New York State. A total of 9,313 newborns with congenital malformations and 17,802 healthy controls living in proximity to 590 hazardous waste sites in 1983 and 1984 were evaluated. After the authors controlled for several possible confounding factors, results indicated that maternal proximity to hazardous waste sites may carry a small additional risk of bearing children with congenital malformations (odds ratio (OR) = 1.12, 95% confidence interval (Cl) 1.06-1.18). Higher malformation rates were associated with both a higher exposure risk (no exposure risk: OR = 1.00; low exposure risk: OR = 1.09, 95% Cl 1.04-1.15; high exposure risk: OR = 1.63, 95% Cl 1.34-1.99) and documentation of off-site chemical leaks (not exposed: OR = 1.00; exposed, but no leaks at site: OR = 1.08, 95% Cl 1.02-1.15; exposed, and leaks found at site: OR = 1.17, 95% Cl 1.08-1.27). The increased rates detected may be important in terms of their public health implications. Further research is necessary to strengthen causal inferences regarding the teratogenicity, of waste site exposure.

Adolescent↗
PubMed1991

Clinical note: childhood neurotic disorders with a sexual content need not imply child sexual abuse.

Two cases are described of childhood obsessional states in which the content of the symptomatology led parents and professionals to suspect child sexual abuse. Following assessment it was felt, on the balance of probabilities, unlikely that child sexual abuse had occurred in either case. Both children had previously engaged in "sex play" with peers. Maternal attitudes to sexuality were felt to have influenced their daughters' views about sexual behaviour and to have contributed to the children's guilt feelings. Response to appropriate treatment was rapid and has been sustained in the short-term. The importance of avoiding lengthy and possibly damaging assessment procedures in such cases is discussed.

Behavior Therapy↗
PubMed1988

Milk-induced analgesia and comforting in 10-day-old rats: opioid mediation.

The effects of slow intraoral milk infusions on the opioid-mediated behaviors of ultrasonic vocalizations and paw removal from a hot plate (48-49 degrees C) were evaluated in 10-day-old rats. Milk reduced distress vocalization by circa 30% while increasing paw lift latencies by about 60%. Alterations in both behaviors were fully reversed by naltrexone (0.5 mg/kg) pretreatments. These data demonstrate the calming and analgesic effects of milk. Implications for a possible role of opioid peptides in mother-young relationships are discussed.

Acoustic Stimulation↗
PubMed1987

Interactions between sucrose, pain and isolation distress.

Two experiments were conducted that establish an opioid-based, functional-relationship between the taste of sucrose, pain threshold and distress vocalization in isolated 10-day-old albino rats. In the first experiment intraoral infusion of sucrose virtually doubled heat-withdrawal latencies. This elevation was naltrexone (0.5 mg/kg b.wt.) reversible. In the second experiment sucrose infusions caused a rapid and sustained diminution of distress vocalizations in rats totally isolated from dam and siblings. These are the first demonstrations of a causal relationship between a positive affective system and ones mediating pain and stress.

Animals↗
PubMed1986

Computed tomography: the investigation of choice for aortic dissection?

Computed tomography has become established as complementary to aortography in the investigation of patients with suspected aortic dissection. Two cases of dissecting aneurysm are reported in which extensive aortography failed to show evidence of dissection. In both cases dissection was demonstrated by computed tomography. The diagnosis was confirmed in one case at operation and in the other case by follow up. It is suggested that computed tomography is the diagnostic method of first choice in aortic dissection.

Aged↗
PubMed1986

Hibernoma: a patient examined by CT.

We describe the computed tomographic (CT) findings in a patient with a hibernoma of the thigh, a rare tumor of brown fat. There are no specific features to allow differentiation from the more common low grade liposarcoma. This is in agreement with the only other published report of the CT features of hibernoma. Although preoperative diagnosis requires biopsy, CT is of value in detecting fatty tumors and in preoperative planning.

Adipose Tissue, Brown↗
PubMed1985

Urachal cancer.

Explore the source record for details and available documents.

Humans↗
PubMed1983

Prevalence of clinical babesiosis in an area in north Co Meath, Ireland.

A survey of clinical babesiosis was carried out in an area serviced by a veterinary practice in Oldcastle, Co Meath. Data were collected from the day books of the practice from 1970 to 1981 and from questionnaires and visits to farmers. Clinical incidence ranged between 3.2 and 4.9 per cent, which was very high compared with figures from Northern Ireland and Devon. Mortality rates were found to range from 7.3 to 14.5 per cent. The seasonality of cases and the age of animals most affected were found to conform to the findings of most earlier studies. The view of the veterinary surgeons that the prevalence of relatively unresponsive cases has increased markedly over the last 12 years was supported by data on the number of revisits and blood transfusions carried out. Cows seemed to be more involved in this phenomenon than other age groups. Although the veterinary surgeons treat less than a third of the cases that occur in the area this seems to be a fairly constant proportion and it is concluded that their day books provide valuable information on the incidence of babesiosis.

Age Factors↗
PubMed1978

Studies on candidate reference preparations of rabies vaccine.

Two candidate reference rabies vaccines were tested in a collaborative study involving seven laboratories. Using four different testing procedures it was determined that both vaccine preparations were highly potent and demonstrated satisfactory stability in the thermal degradation test.

Animals↗
PubMed1975

Coarctation of the abdominal aorta with multiple aneurysms. Operative correction.

An 11-year-old asymptomatic girl with hypertension was found to have coarctation of the abdominal aorta with four aneurysms in or adjacent to the hypoplastic segment of aorta. Operative treatment included insertion of a thoracoabdominal aortic bypass graft and resection of the aneurysms. The association of abdominal coarctation and aneurysm formation is reviewed and the rationale for therapy discussed.

Aorta, Abdominal↗
PubMedDate not supplied

Bilateral primary renal lymphoma.

BACKGROUND: Primary renal lymphoma is rare with no well-defined diagnostic criteria. AIM: To describe the first reported case of bilateral and primary renal lymphoma and describe diagnostic criteria. RESULT AND CONCLUSION: If a diagnosis of primary renal lymphoma is to be considered, then specific diagnostic criteria (as outlined) must first be satisfied.

Female↗