PubMed Health⌕ Search

Biomedical subjects

E Fluur

Publications and source records attributed to E Fluur.

At least 19 recordsLinked to original sources
PubMed1988

Rotatory test in otoneurology.

A series of rotatory tests are described, by which it is possible to activate the ocolomotor system by visual as well as by vestibular stimuli, either separately or in combination. The visual-oculomotor system was studied by means of rotation with 10 degrees constant speed for 10 s in either direction. Pursuit movements and saccades were also studied. The vestibulooculomotor system was studied by acceleration behind closed eyes with 10 degrees/s2 up to 100 degrees, immediately followed by a similar deceleration. Normal and pathological cases are presented. A combined visual-vestibular stimulation was performed with the same kind of acceleration-deceleration but with eyes open. Acceleration demonstrated the summation effect of visual and vestibular input to the vestibular nuclei. The deceleration revealed the cerebellar ability to suppress the vestibular output. Normal and pathological cases are demonstrated. Finally, a combined rotation was introduced, informing us about the vestibular reaction, the visual-vestibular summation, the optokinetic reactions, and the cerebello-vestibular suppression. Normal and pathological cases are described.

Acceleration↗
PubMed1981

Mechanisms underlying modulations of thermal nystagmic responses in parabolic flight.

In six subjects nystagmography was used to compare the responses to cold calorization of one horizontal semicircular canal under ground-based and parabolic flight conditions. On the ground the expected individual differences in primary nystagmic responses were observed; only one subject manifested a brief weak secondary nystagmus. Aloft, the irrigation was carried out in straight-and-level flight prior to a pushover (half-parabola) that initiated a series of four to nine typical parabolas in a modified KC-135 aircraft. Thereafter, the free-fall phases of the parabolas furnished a zero baseline for measuring weight differences in endolymph due to changes in gravitoinertial force. In all subjects a secondary nystagmus was generated in addition to the primary nystagmus during the course of the parabolic maneuvers. The slow phase of the secondary nystagmus rarely exceeded 10 mm per sec. Evidence is presented that secondary nystagmus arises as a direction-specific adaptation effect countering the primary nystagmic response. Three stages were recognizable: first, when primary and secondary nystagmus alternated in step with the high and low force phases of the parabolas; second, after disappearance of primary nystagmus when secondary nystagmus appeared alone and was modulated by the changes in force; and third, when the secondary nystagmus present became independent of the highest gravitoinertial forces generated. Great individual differences were observed, suggesting that with large departures of the cupula from its functional rest position there are large individual variations in rate of restoration.

Adult↗
PubMed1976

Hearing loss as a sequel to chloramphenicol and ampicillin treatment of Haemophilus influenzae meningitis.

20 patients with Haemophilus influenzae meningitis who had been treated with chloramphenicol over the period 1959-1970 and 23 patients who had been treated with ampicillin over the period 1968-1974 were re-examined by hearing tests in 1975. In all the cases the two agents had been given initially by the parenteral route, chloramphenicol in doses varying between 50 and 150 (averaging 101) mg/kg/day and ampicillin in doses varying between 125 and 350 (averaging 229) mg/kg/day. Five of the 20 patients in the chloramphenicol group were found to be deaf on one ear, whereas 1 of the 23 patients in the ampicillin group was completely deaf. A further 3 in the chloramphenicol group and 1 in the ampicillin group had slight sensorineural hearing loss on one ear. Only in 2 of the 6 deaf patients was the loss discovered during the time of hospital care. The present study has not provided any evidence supporting the recently reported observation (Gamstorp and Klockhoff, 1974) that the frequency of hearing loss might be higher after ampicillin than after chloramphenicol treatment for H. influenzae meningitis.

Adolescent↗