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Biomedical subjects

E Freiesleben

Publications and source records attributed to E Freiesleben.

18 recordsLinked to original sources
PubMed1980

A critical review of platelet yield by Haemonetics 30 . Based on literature and own observations.

By means of a haemonetics 30 cell separator platelets were collected for transfusion purposes from 18 different blood donors. A median yield of 5.7 X 10(11) platelets was obtained. The yield of platelets was found to be linearly related to the donors' initial platelet counts. The procedures were standardized by using one size of bowl (225 ml), performing 10 cycles per procedure, and performing all cycles as uniformly as possible. The median time per procedure was 118 min. Mild donor reactions were seen in 8 donors (44%) consisting of circumoral tingling. The decrement in the donors' platelet count was 86 X 10(9)/1, 37% of the initial platelet counts. The choice of the bowl size of 225 ml is motivated. The absurdity of the expression of yield pe h of processing, and of yield per 1 of blood processed is discussed. Furthermore, it is shown, that neither the fall in haematocrit nor the fall in the platelet count during the procedure are linear. The formulas commonly used for calculating the blood volume and platelet extraction efficiency, which are based on these assumptions, cannot therefore, in our opinion, be used.

Blood Donors↗
PubMed1978

ABO and Rh phenotyping of foetal blood obtained by foetoscopy.

Blood samples taken from the foetus by foetoscopy early in the 2nd trimester of pregnancy can be used for reliable blood grouping. However, the sampling technique is not perfect. In 5 out of 15 pregnant women, no foetal blood was obtained, although between 1 and 10 samples were taken on each occasion. One-third of 56 samples from the 10 women contained foetal blood. Contamination of samples with amniotic fluid varied, but did not interfere with the blood grouping. ABO and Rh typing of the foetus was possible even if the samples were contaminated with large amounts of maternal blood. In nine cases, blood grouping of the foetus was performed on red cells from foetoscopy samples. Control blood samples from the foetus following abortion were obtained in seven of these cases, and the foetoscopic results were confirmed.

ABO Blood-Group System↗