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Biomedical subjects

E G Liabakh

Publications and source records attributed to E G Liabakh.

8 recordsLinked to original sources

[Oxygen tension in rat mixed skeletal muscle at a low diffusion coefficient].

Numerical simulation of the oxygen low diffusion coefficient (1.3.10-6 cm/sec) in a skeletal muscle with three types of fibres with different oxygen demands, has revealed: 1) an enlarged vascularisation of a fibre with high oxygen demand prevents the development of hypoxia because of shortening of the ways of oxygen diffusion from capillaries; 2) in a muscle with external layers consisting mainly of white fibres with low oxygen demand and deep layers of red fibres, the pO2 in the tissue and in the blood flowing from the layers, decrease with the depth.

Animals↗

[Muscle oxygen supply following total blood replacement with an oxygen-transporting blood substitute].

Mathematical model revealed the O2 distribution within the microspace among capillaries under conditions of resting and contracting muscle. The blood--substitute did not provide complete saturation of the muscle with oxygen in initial state. Nevertheless involvement of physiological responses compensating for lack of the O2 in the muscle (acceleration of blood flow and mobilizing of reserve capillaries) aided to complete saturation of the muscle with oxygen and maintained a certain level of contractile activity.

Blood Flow Velocity↗