Biomedical subjects
Publications and source records attributed to E G Shifrin.
The extremely rare case of ruptured abdominal aortic aneurysm of inflammatory nature in patient with discovered acute myelomonoblastic leukemia is presented. The difficult problems arising from these, frequently terminal diseases, are discussed.
We present three patients with successful surgical repair of abdominal aortic aneurysms with signs of imminent rupture in octogenarians. The patients presented with evidence of severe left ventricular dysfunction and reduced compliance either before or during surgery. Extremely cautious delivery of fluids and of after-load reducing agents was employed under the guidance of measurements of cardiac output and filling pressures from a pulmonary arterial catheter inserted prior to surgery.
A study was made of delayed embolectomy in 45 patients (55 limbs). In 5 patients (11%) the cause of arterial embolization was rheumatic heart disease, and 40 patients (89%) suffered from atherosclerotic cardiovascular disease. The study was divided into 3 phases: I (1960-1964), II (1965-1974) and III (1975-1981). In phases II and III surgery was carried out using the Fogarty catheter technique. In 5 patients the embolus was located in the upper extremity. Seven patients died and 8 major amputations were performed within 30 days of surgery. Use of the Fogarty catheter technique and persistent anticoagulant therapy effected 71.8% limb salvage in phase II and 91.6% limb salvage in phase III. Successful revascularization was achieved in 70.9% of the limbs in which peripheral emboli had occurred on an average of 2.7 days prior to surgical intervention. A theoretical basis for the late development of the acute embolic onset is presented.
Between 1979 and 1985 11 selected patients underwent axilloaxillary and carotid-subclavian bypass grafting [dacron or Gore-Tex (USA), 8 mm inner diameter]. Nine patients had lesions in the left subclavian artery and two patients presented with innominate artery obstruction with subclavian-carotid recovery phenomenon. All patients were symptomatic before surgery, and all were relieved of both cerebrovascular and upper extremity ischemic symptoms following surgery. Early graft patency has been excellent. There has been no mortality or serious postoperative complications. Two patients developed late graft thrombosis with recurrent ischemia of the left upper extremity, but there were no neurological symptoms. There has been a follow-up period of up to 6.5 years (mean 38.4 months.) It would appear that the appropriate extrathoracic route of revascularization is the procedure of choice for symptomatic patients with subclavian steal and subclavian-carotid recovery phenomenon.
Arterio-venous fistula following Fogarty catheter embolectomy is a rare but dangerous complication. The case of a male patient in whom such a fistula was repaired surgically is described. Aggressive approach in the treatment of this severe condition to prevent unnecessary limb loss is advocated. The pertinent literature is reviewed.
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Percutaneous transluminal angioplasty with the Gruntzig balloon catheter was undertaken in 12 patients with chronic lower limb ischemia. As judged by postdilatation angiography, the procedure was successful in 11 patients (91.6%). Nine patients were either free of symptoms or very significantly improved at follow-up, one to five months after angioplasty. Indications for angioplasty and the technique are described and discussed.