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Biomedical subjects

E G White

Publications and source records attributed to E G White.

10 recordsLinked to original sources

Torsades de pointes ventricular tachycardia and terodiline.

We report five patients (four women, one man; mean age 74 years, range 55-87) taking terodiline who had torsades de pointes ventricular tachycardia associated with prolongation of the QT interval. The QT interval was normal before the introduction of terodiline in three patients and returned to normal after terodiline withdrawal in four. Atrioventricular conduction disturbance or bradycardia were evident in all patients. Terodiline should be prescribed with caution to elderly patients.

Aged

Footcare for very elderly people: a community survey.

We have assessed foot problems of, and chiropody provision for, 96 people aged 80 years and over who were living at home. Seventy-seven per cent had difficulty cutting their toenails and 30% complained of pain in the feet. The commonest foot problems were corns or callus, abnormal nails, hallux valgus and other toe abnormalities. Only six subjects had normal healthy feet. Of the 47 people receiving chiropody, two-thirds were being seen privately. Private chiropody tended to be performed in the home and was more frequent than National Health Service (NHS) treatment. Fifteen subjects needed but were not having chiropody. Foot problems are common in the very old. We suggest that doctors and nurses should ask old people regularly about problems cutting nails and pain in the feet. At present the provision of chiropody for old people is inadequate and ways of improving foot care must be found.

Aged

Special footwear.

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Consumer Behavior

Haematuria occurring during antirheumatoid therapy.

One hundred and ninety-one patients treated with gold and penicillamine over a seven-year period were reviewed retrospectively for the occurrence of haematuria. Over this period 10% had shown haematuria, and in over half of these an identifiable cause was found. In the remaining patients, a clear relationship with their treatment seemed likely in only two. Penicillamine therapy was discontinued in all patients with unexplained haematuria, but two patients have continued to show haematuria. Gold therapy has been continued in the presence of haematuria without ill effect. There has been no deterioration in renal function in those patients who have continued to show unexplained haematuria and at no time was proteinuria an accompanying feature.

Adult