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E G de Reyners

Publications and source records attributed to E G de Reyners.

5 recordsLinked to original sources
PubMed1978

[Development of equilibrium of glial populations in the cerebral cortex of lead intoxicated rats].

The three types of glial cells (astrocytes, oligodendrocytes and microglia) were counted at 2 different ages in normal and lead intoxicated animals (on a 0.5% Pb2+ diet) and were found to vary differently with respect to age and lead treatment. Satellisation of nerve cells by glia also displays a different pattern : whereas usually at 3 month age, the neurons are surrounded by oligodendrocytes, they appear more often encapsulated by microglia after lead treatment. It is postulated that changes in glial populations and their relationship to nerve cells could provide a sensitive indicator of lead encephalopathy.

Aging↗
PubMed1976

Hypervascularization of the cerebral cortex in lead-induced encephalopathy.

Pregnant rats were fed a diet containing 1.8% lead acetate for 8 days before delivery until the young were 3 month old. The density of the cerebral cortex capillaries of the infant rats and their convolution rate were studied morphometrically and noted to increase significantly according to the duration of lead treatment, as demonstrated by two-way analysis of variance. On the other hand, the thickness of the cortex reduced progressively. The increase of both capillary density and convolution rate is supposed to be related with this involution of cortex. This provides a quantitative insight of the previously described 'capillary activation' phenomenon, caused by lead encephalopathy and reveals it as a significant sequel of saturnine action.

Age Factors↗
PubMed1975

An ultrastructural quantitative method for the evaluation of the permeability to horseradish peroxidase of cerebral cortex endothelial cells of the rat.

A quantitative method for the evaluation of the importance of pinocytotic phenomena in cerebral cortex capillaries is proposed. The method involved the counting of labeled "caveolae intracellulares" in endothelia cells with the use of horseradish peroxidase as a tracer molecule. A mean pinocytotic value per capillary is then computed. It is demonstrated that the value obtained after irradiation of the brain is higher than in control animals. This information may provide an ultrastructural quantitative approach to the analysis of the blood brain barrier and of other problems related to vascular permeability of the cerebral cortex.

Animals↗