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Biomedical subjects

E Galindez

Publications and source records attributed to E Galindez.

7 recordsLinked to original sources

[Chronic monoarthritis caused by osteoid osteoma].

Osteoid osteoma is a nonmalignant tumour that rarely localizes intraarticularly. When this happens, the tumour provokes arthritis and its recognition is delayed from months to years. We report the case of a 34 year old man with a previously known HIV infection, but no evidence of immunosuppression. He develops a chronic monoarthritis of the left elbow that is initially interpreted as infectious disease. CT provides diagnostic suspicion of osteoma, that is confirmed by pathologic examination two years after the onset of the clinical complaints. CT is the radiologic technique of election in the evaluation of osteoid osteoma. Synovitis is interpreted in the literature as secondary to prostaglandin secretion by the tumour.

Acquired Immunodeficiency Syndrome↗

Effect of ouabain in therapeutic concentrations on K+ exchange and contraction of human and rabbit myocardium.

1. Experiments were undertakn on strips of human atrial and ventricular muscle, on right ventricular rabbit papillary muscles and on the rabbit interventricular septum. 2. In all preparations an increase of developed tension after 30 min exposure to ouabain was apparent only at or above a concentration of 10(-7) mol/l (73 micrograms/l). 3. In the rabbit septum there was a net loss of potassium on exposure to ouabain if the concentration was greater than 10(-7) mol/l. There was no net loss, or gain, of potassium at lower concentrations. Loss of potassium, indicating inhibition of the sodium pump, could not be dissociated from the positive inotropic effect of ouabain. 4. The greater sensitivity to ouabain of human myocardium in vivo (10(-8) mol/l) than in vitro (10(-7) mol/l) may be due to cellular changes occurring in isolated preparations.

Action Potentials↗

Tetralogy of Fallot with subpulmonary ventricular septal defect.

Among a total of 608 patients with tetralogy of Fallot, 35 with tetralogy and subpulmonary ventricular septal defect (VSD) have undergone intracardiac repair at the Children's Hospital, Buenos Aires. The crista supraventricular was absent in 62.9% of these patients; it was hypoplastic in 37.1%. Only 3 patients (8.6%) were severely cyanotic and required operation in infancy. The main and left and right pulmonary arteries were relatively large in all but 1 patient. Nevertheless, patch-graft enlargement across the pulmonary valve ring was necessary in 20 (57.1%). We believe that closure of the subpulmonary VSD increase the apparent severity of the pulmonary stenosis and necessitates patch-graft enlargement in patients in whom the appearance of the right ventricular outflow tract before repair would not have suggested its need.

Adolescent↗

[Interventricular communications with aortic insufficiency surgical considerations].

The authors report a series of 11 patients with ventricular septal defect associated with aortic incompetence who underwent surgery between 1963 and March 1976. Separate consideration is given to the operations performed before and after 1972. 5 patients were operated on during the first period, with only mediocre results. At this time, the technique of valvuloplasty did not appear to be the right one. During the second period, 6 patients were operated on. In five of them the technique of Plauth, Frater, Spencer and Trusler was used. All these patients have a satisfactory result. The last of the series had an abnormally low commissure, and the adjacent valves were protuberant, and thickened, so that a valvular replacement was carried out. The operation of choice for a ventricular septal defect associated with aortic incompetence is valvuloplasty with closure of the defect. The following criteria are necessary indications for this type of surgery: --the aortic incompetence must be secondary to the prolapse of a valve; --the aortic valve must have three cusps. An early operation makes the valvuloplasty easier, and avoids the problems of damage to the left ventricle from a persistant and progressive aortic incompetence.

Adolescent↗