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Biomedical subjects

E Gallagher

Publications and source records attributed to E Gallagher.

22 records · Page 2Linked to original sources
PubMedDate not supplied

Management of a widely disseminated skin rash.

T.J.'s case was interesting from the standpoint of both diagnosis and management. The recommended treatment for this drug reaction was prednisone: however, the use of a steroid in a patient who is neutropenic and has a fever is risky because the because the steroid can mask the symptoms of infection (e.g., fever). Administration of prednisone did help, and the patient experienced a rapid resolution of the skin rash. T.J. will need to avoid the use of these antibiotic agents in the future. Because it is unknown which antibiotic, vancomycin or ceftazidime, caused the allergic reaction, both medicines should be avoided. The decision to rechallenge a patient with a specific drug must be made on an individual basis. Rechallenging of a drug in patients who have had urticarial, bullous, or erythema multiforme-like eruptions can be very dangerous (Padial et al., 2000). Pinpointing the cause of a skin rash can be puzzling. Always ask the patient "Do you take any medicine for any condition (including aspirin, laxatives, vitamins, etc.)? Have you received any shots any shots in the last month?" Keep in mind that any chemical that is ingested can cause a cutaneous drug eruption.

Aged↗
PubMedDate not supplied

Prevalence of hepatitis A IgG in Irish international travellers.

The authors have studied the sero-conversion levels of Irish international travellers over the past 6 years with regard to Hepatitis A IgG levels. The rate of sero-conversion is significantly associated with patient age (x2 = 77.8, df = 1, p < 0.0001). There was no significant difference in the antibody levels between males and females. The results show that a large proportion of younger people travelling to developing countries are unprotected against Hepatitis A. Also approximately 30% of travellers over the age of 40 years have not seroconverted from previous exposure and therefore remain at risk. The mortality associated with Hepatitis A is in high risk groups. Therefore vaccination should be considered.

Adult↗