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Biomedical subjects

E Ger

Publications and source records attributed to E Ger.

16 recordsLinked to original sources
PubMed2004

High-dose exposure to valsartan with suicidal intention.

Valsartan is a strong angiotensin receptor inhibitor specific for the angiotensin I receptor, which has been proven safe and well-tolerated in clinical trials. We were able to confirm its safety and tolerability in a case of high-dose exposure to valsartan with suicidal intention. A 25-year-old, fully conscious, female patient was brought to our hospital by relatives on July 24, 2001, at 9:15 p.m. following intake of a high dose of valsartan. It was established that she had taken 28 Diovan 80 mg tablets (2.24 g) 5 hours before admission to the hospital. Her clinical condition at the time of admission was good and did not deteriorate after admission. During the follow-up, her blood pressure never fell below 90/60 mmHg. The only complaint she had were painful muscle cramps which, with only supportive therapy, disappeared spontaneously over 2 days, and her blood pressure also returned to normal during this period. This report demonstrates the effect/side effect profile of valsartan when taken at a high dose, not achievable in a clinical trial.

Adult↗
PubMed1991

The management of trigger thumb in children.

Trigger thumb in children is an uncommon condition. We reviewed 41 patients with 53 trigger thumbs. Although the current accepted approach to the treatment of congenital trigger thumbs is a prolonged period of observation, our findings indicate that all of our patients eventually required surgical release of the flexor pollicis longus tendon. Waiting 3 years before a surgical release was done did not affect the surgical result.

Child↗
PubMed1991

[Social and functional results of brachial plexus birth injury].

Long-term results of obstetrical brachial plexus injury were studied. The medical records of 10 females and 9 males (range 16-59 years, mean 27.8) who responded to a questionnaire were reviewed. According to the responses, they all had been leading normal lives, despite various degrees of impairment.

Adolescent↗
PubMed1987

Evaluation of a uniform operative technique to treat syndactyly.

Twenty-two patients with upper extremity syndactyly (58 webs) have been treated in the last decade (1976 to 1985) by one hand surgeon using one technique. Nineteen patients had syndrome complexes or other associated anomalies that made treatment more difficult. The postoperative follow-up averaged 4 years. The rate of complications that necessitated repeat operations (5% of the treated webs) was relatively low in comparison with those in other series. We attribute this to better timing of the procedure and progressive experience gained by one surgeon using the same procedure.

Child↗
PubMed1987

Double fingernails on the small fingers.

This report describes the unusual presence of dorsal skin and a fingernail on the palmar surface of both small fingers, with a normal nail on the dorsal surface. This child has a normal karyotype. There has been one previous report in the literature of a similar anomaly associated with a chromosome 6 abnormality.

Chromosomes, Human, Pair 6↗
PubMed1984

Osteoid osteoma of the proximal femur: new techniques in diagnosis and treatment.

The nonspecific symptoms and radiographic findings associated with osteoid osteoma in the proximal femur mimic inflammatory conditions and delay diagnosis. A review of four cases showed high resolution computerized axial tomography in conjunction with a radioisotope bone scan best demarcated the location and size of the lesion. The combination of careful preoperative localization and intraoperative use of a radiation probe made adequate resection possible while limiting the amount of bone excised. This technique eliminated the need for internal fixation and reduced the duration of the recovery period.

Adult↗
PubMed1979

Evaluation of the operative treatment of syndactyly.

A review of the records of 61 patients with 176 surgically treated webs was completed to evaluate the results of the different operative techniques used to separate the fingers. The postoperative follow-up period averaged 14 years, with a range from 2 to 38 years. The patients were assessed in two groups: those with major associated anomalies and those in whom syndactyly was the principal anomaly. Recurrence of the webs and flexion and extension contractures occurred more often when split-thickness grafts were used. To obtain a satisfactory result, a second procedure was necessary in 59% of patients with major associated anomalies, and in 30% of the patients who had syndactyly as the principal abnormality. Two types of patients were found to require subsequent operations: children treated prior to 18 months of age and those with complex syndactyly.

Abnormalities, Multiple↗
PubMed1979

Congenital radial head dislocation.

Fifty patients with 77 congenitally dislocated radial heads were reviewed to assess the diagnostic features, functional limitations, symptomatology, and results of treatment. Twenty-three patients had associated anomalies of the affected upper extremity, and 35 had anomalies in other parts of the body. In six patients no other anomaly was found, all six had bilateral involvement. No patient had congenital radial head dislocation as a unilateral isolated anomaly, and therefore we doubt its existence. Functional limitation with congenital radial head dislocation is minimal and pain is uncommon. Radial head excision relieves pain and improves appearance: however, it does not increase motion.

Abnormalities, Multiple↗
PubMed1977

Bone cement and antibiotics.

Antibiotics of various kinds were added to the powdered polymer of methylmethacrylate in a concentration of 1 g antibiotic/40 g cement, prior to the addition of the liquid monomer. Specimens were subjected to mechanical testing by loading them in direct compression on a 20-ton Instron Universal Testing Machine, and load deflection curves were recorded. It was found that the addition of antibiotics does have an effect on the mechanical strength of the cement--the loss was small, less than 10% for both the compressive strength and the elastic modulus, provided the antibiotic was in powder form. Liquid antibiotics resulted in a greater loss of the compressive strength of the mixtures, but specimens tended to be less porous. In vitro studies of the antibiotic properties of the mixtures demonstrated potent antibacterial activity in all the antibiotics tested, except chloramphenicol. Possible clinical applications are discussed. Further in vivo studies are needed before widespread clinical use can be advocated.

Anti-Bacterial Agents↗
PubMedDate not supplied

Congenital constriction band syndrome.

A retrospective study of 55 patients with congenital constriction band syndrome was performed. Multiple extremity involvement was found to be the most common clinical feature associated with the disease, and 34% of the patients studied were premature at birth. Malformations included constriction bands, clubfoot, intrauterine amputation, syndactyly, and acrosyndactyly (fenestrated syndactyly). The extremities were most often affected distally, involving the longer central fingers and medial two toes. More proximal involvement with constriction bands was associated with a higher frequency of neurologic deficit. Significant leg-length discrepancy exceeding 2.5 cm was seen in 9 of 38 patients (24%) with lower extremity involvement, a condition that has not been previously reported.

Abnormalities, Multiple↗