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Biomedical subjects

E Gerke

Publications and source records attributed to E Gerke.

At least 19 recordsLinked to original sources

[Sclera fixation of posterior chamber lenses. Indications, technique and results].

Over 18 months we implanted posterior chamber lenses in 40 eyes using transscleral suturing. The indication for this technique was the absence of capsular support, in most cases due to previous cataract surgery and/or trauma. A uniform procedure was used. After a medium follow-up of 9 months the major complications were as follows: immediately after the operation transient keratopathia was present in a third of the cases; 6 eyes showed iritis, which persisted in 4 eyes. Other late complications were cystoid macular edema in 2 cases and central vein occlusion, retinal detachment and recurrent iritis in single cases. Despite these complications the functional results were favorable in 32 eyes with a best corrected vision of 6/12 or better. Poor visual outcome could be related to the operative procedure in 2 eyes and to pre-existing pathology in the remaining 6 cases. We conclude that the operative technique should be improved to reduce complications.

Follow-Up Studies

[Daunomycin in vitrectomy of complicated diabetic retinal detachment].

Fourteen eyes with combined traction and rhegmatogenous retinal detachments from proliferative diabetic retinopathy were treated with pars plana vitrectomy (PPV) and daunomycin applied to the vitreous cavity using the technique described by Wiedemann et al. for the treatment of proliferative retinopathy. The operations were completed by filling the vitreous with silicone. The aim of our study was to investigate the effect of daunomycin and the reproliferation rate. After a follow-up period of at least 3 months, the post-operative results were compared with a control group of similar eyes treated with PPV and silicone tamponade alone. No evidence was found to the effect that daunomycin affects the rate of reproliferation.

Adult

Red krypton and blue-green argon laser diabetic panretinal photocoagulation.

Eyes with three or four diabetic retinopathy risk factors received laser panretinal photocoagulation with random selection of either blue-green argon (42 eyes) or red krypton (40 eyes) laser to determine if one laser was superior to the other. After 6 months, visual acuity preservation or improvement was obtained in 33 (79%) argon- and 34 (84%) krypton-treated eyes. Peripheral IV-4e visual field constriction of 7% occurred with argon and 10% with krypton. Vitreous hemorrhaging after treatment occurred in 1 argon- and in 6 krypton-treated eyes. Complete disc neovascular regression was obtained in 27 (67%) of 40 argon- and 19 (56%) of 34 krypton-treated eyes, with partial regression occurring in 8 (20%) argon- and 8 (24%) krypton-treated eyes. The two treatments produced essentially equal results.

Adolescent

[Retinal macroaneurysm as a cause of hemorrhage into the vitreous body].

Retinal macroaneurysms are often misdiagnosed. Although the vast majority of cases are symptom-free or lead to perianeurysmal exudates and bleeding, a few rare cases show rupture and bleeding into the vitreous body. In four patients who had been referred because of acute visual deterioration caused by a vitreous hemorrhage of unknown origin, the peripheral fundus could initially be examined ophthalmoscopally. Six weeks later, bleeding recurred in one eye, making examination impossible. Ultrasound examinations showed that the central retinae of all four eyes were not detached. In one case, a small, solid elevation close to the macula was observed at B-scan. Following spontaneous resorption of the vitreous hemorrhages, fluorescein angiography showed one macroaneurysm in each of two eyes and two macroaneurysms in the other two eyes, located in each case in the temporal arteries. Following laser treatment in 3 of the 4 cases, no further hemorrhages were observed in any of the patients over a follow-up period of 4 to 15 months.

Adolescent

[Photocoagulation in diabetic rubeosis iridis and neovascular glaucoma].

This retrospective study was performed to examine the effect of retinal coagulation on the course of iris neovascularization and neovascular glaucoma in patients with diabetic retinopathy. Sixty-four eyes in 42 patients were examined. Following retinal coagulation iris neovascularization regressed in 47 eyes (73%), while 17 eyes (27%) showed no improvement. In eyes with neovascular glaucoma, a drop in intraocular pressure was noted. Visual acuity decreased in 60% of the treated eyes. Regression of iris neovascularization was related to the number of burns applied.

Diabetic Retinopathy

Tumor regression after photocoagulation of malignant melanomas of the choroid: an ultrasonographic study.

Ultrasonography was performed in 24 eyes harboring malignant melanomas of the choroid to study tumor regression after xenon-arc photocoagulation at periodic intervals after each photocoagulation session. Ophthalmoscopically, 20 (83%) eyes revealed a complete regression of the tumor after 3 months to 3 years of treatment. However, ultrasonography revealed complete tumor regression in only 13 (65%) out of these 20 eyes while the remaining 7 (35%) 9 eyes had a residual tumor prominence of 0.75-1 microsecond. 14 (70%) out of 20 tumors were completely regressed 1 year after photocoagulation treatment. Most of the eyes revealed complete disappearance of the tumor after 3-5 photocoagulation sessions. Though 4 tumors which did not respond to photocoagulation treatment were located in the central temporal retina within the vascular arcade, no statistically significant difference could be seen between tumor regression and location of the tumor. Complete tumor regression was seen in 4 out of 5 eyes after encircling coagulation alone while 16 out of 19 eyes revealed complete tumor regression after addition of direct treatment of the tumor. Photocoagulation appeared to be a useful tool in the treatment of small choroidal melanomas.

Adolescent

[Vitrectomy and subsequent photocoagulation in proliferative diabetic retinopathy with vitreous hemorrhage].

Forty eyes in 39 patients with proliferative diabetic retinopathy, vitreal hemorrhage and progressive neovascularization in at least 3 fundus quadrants were treated with panretinal xenon photocoagulation immediately after pars plana vitrectomy. Lens extraction was performed on 7 eyes and 2 eyes were aphakic. Six months after treatment, 68% of the eyes showed an improvement in vision, 25% had vitreal rebleeding and 11% developed rubeosis iridis. While treatment had no effect on peripheral rubeosis iridis in 5 eyes, all 7 eyes with pupillary rubeosis iridis showed complete regression. The results indicate the clinical value of combining, pars plana vitrectomy with panretinal xenon photocoagulation in selected patients.

Adult