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Biomedical subjects

E Gibert

Publications and source records attributed to E Gibert.

3 recordsLinked to original sources

[Juvenile xanthogranuloma in a flat xanthoma].

A case of juvenile xanthogranuloma located on a plane xanthoma plaque in the left flank of a seven months old child is reported. Histologically we observe a typical pattern of JXG in the center of the lesion and foamy cells exclusively around the capillary vessels in the peripheric areas of the lesion. We consider that the same etiopathogenic mechanisms implicated in the JXG will produce the clinical and histologic appearance of plane xanthoma around it.

Female

[Cellular immunity in polymorphous light eruption].

Lymphocytic-cell subsets (T total, T helper, T suppressor-cells) have been studied with Monoclonal Antibodies (OKT-3, OKT-4, OKT-8) in 21 patients with Polymorphous light Eruption in inactive phase and have been compared with 13 controls. The results shvon normal cell figures (T total, helper and suppressor). However, when observing the ratio between T helper cells and T suppressor cells, a slight decrease in this ratio is appreciated, which would correspond to a relative increase of suppressor cells. These results are similar to those obtained for the inactive S. L. E. (9).

Humans

[Lucio's leprosy].

A case of diffuse lepromatous leprosy with lepra reaction type II-Lucio's phenomenon-in a 24 years old male patient is reported. The histological examination of the necrotic lesions and of the apparently normal skin showed the presence of dense perivascular and perianexial lymphohystiocitic infiltrates with great quantities of bacilli. The first biopsy did not show a picture a leuccocytoclastic vasculitis but only areas of necrosis. The immunofluorescence studies revealed on direct examination complement deposits on vessel walls. The complement levels in blood were lowered and circulating inmunecomplexes were also detected. These data confirm the opinion that Lucio's phenomenon is caused by circulating inmunecomplexes fixed on dermal vessel walls causing skin necrotic lesions.

Adult