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Biomedical subjects

E Gocár

Publications and source records attributed to E Gocár.

9 recordsLinked to original sources
PubMed1999

[Elastic band ligation in secondary prevention of esophageal varices hemorrhage].

BACKGROUND: Sclerotization of esophageal varices may result in serious esophageal destruction. Elastic band ligation of esophageal varices is recently used in similar indications. AIM: The aim of the study was to evaluate in a pilot study the efficacy and safety of elastic band ligation for secondary prevention of bleeding from esophageal varices in patients who experienced life-threatening and were not yet treated with elastic band ligation. PATIENTS AND METHODS: Saeed's method of elastic band ligation was used in 10 patients (5 men and 5 women) aged from 16-60, who had already experienced life-threatening esophageal varices hemorrhage. One patient awaiting liver transplantation underwent preventive ligation. RESULTS: Esophageal varices were eradicated in 5 patients, minimum range residual varices remained in 4 patients after ligation. Haemorrhage recurrence was observed in 4 patients and was successfully treated by single urgent sclerotization. Two patients developed neo-varices. The ligation program was stopped in one female patient with mitral stenosis and tricuspidal insufficiency because of stenocardias occurring during ligation. In one session, 4.5 elastic bands in average were applied. The treatment of one patient required 4 sessions during 2.5 months in average. CONCLUSION: Elasic band ligation is an effective and safe method for the treatment of esophageal varices. Short term results are promising. (Tab. 1, Fig. 1, Ref. 18.)

Adolescent↗
PubMed1992

[Antibiotic therapy of infections in patients on dialysis].

The results obtained in treating infections in 53 patients involved in a chronic dialysis-transplantation program are reported. Higher susceptibility to infections and reduced immune functions were observed in dialyzed patients. The problem of the occurrence rate of individual infections was analyzed and infections of the respiratory system, particularly bronchopneumonia, were found to be predominant. No patient died of infection; in two patients the prescribed antibiotic of first choice had to be changed; positive clinical and laboratory effect was recorded in 51 of the 53 patients treated, and after change of the antibiotic in all the patients. Particular regimens of individual antibiotics in dialyzed patients are given along with the dialyzability of the drugs. The best results were obtained with ofloxacin and doxycycline of Czecho-Slovak make in monotherapy, in combined treatment gentamycin an amikacin with cefamezin or with cefotaxim proved to be most effective. Of the 45 pathogenic agents isolated, Staphylococcus aureus, Klebsiella spp, and Acinetobacter lwoffi, which have a good sensitivity to antibiotics, had the highest occurrence rates. (Tab. 4, Ref. 6.).

Anti-Bacterial Agents↗
PubMed1989

[Acute renal insufficiency after the administration of tetracycline and gentamycin].

The clinical course of eight case reports of patients with acute renal failure after administration of nephrotoxic antibiotics--specially of tetracycline and gentamycin--is demonstrated. All patients were suffering on preexisting nephropathy, many of them in stage of chronic renal failure according to various etiopathogenesis. As concomitant factor inducing acute renal failure together with antibiotics are: elderly, hepatopathy, surgical interventions, administration of other nephrotoxic drugs. In 6 patients, where acute renal failure induced by nonreducted doses of antibiotics appeared, the treatment was successful, in five cases due to short term haemodialysis, once conservatively with diuretics and volume diuresis. Two patients died before the therapeutic measures and dialysis could be performed. Algorithms in diagnosis and treatment of chronic renal failure--patients where antibiotic treatment is necessary are discussed.

Acute Kidney Injury↗
PubMed1989

[Ultrasonography of echinococcosis, toxocariasis and cysticercosis of the liver].

The diagnosis of tissue parasitoses has remained complicated until the present time for variability of clinical picture. Their incidence been increasing due to aimed and accidental findings of foci in parenchymal organs employing new methods of visualization such as computer tomography and especially ultrasonography whose advantage is a good detection rate, availability and a possibility to follow the dynamics of parasitosis development. The authors present a survey of ultra-sonographic findings of the liver in cases of tissue parasitoses occurring in Czechoslovakia, while using their own image documentation. If a focal affection in the liver is established the differential diagnosis considerations should also take into account a tissue parasitosis, whose ultrasound picture may be nonspecific.

Cysticercosis↗
PubMed1989

[Elevated indicators of liver metabolism in patients with giardiasis].

The authors present an account on 60 patients where, based on the clinical picture, parasitological examination and laboratory parameters, the diagnosis of giardiasis was established. Among these patients a rise of one or several indicators of liver metabolism was found in 31%. The authors discuss whether the above conditions can be considered hepatitis within the framework of the basic parasitic disease. They eliminated non-parasitic causes (obstruction, HBsAg positive hepatitis, drug hepatitis, toxic hepatopathies) of elevated transaminase and bilirubin levels. For collection of duodenal juice or faeces for parasitological examination they used a gastrofibroscope or rectoscope. After treatment normalization of transaminase and bilirubin serum levels was recorded as well as regression of clinical symptoms and of eosinophilia.

Giardiasis↗