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Biomedical subjects

E Greve

Publications and source records attributed to E Greve.

14 recordsLinked to original sources
PubMed1991

[Additive effect of timolol and the local carbonic anhydrase inhibitor MK-417 (sezolamide)].

MK-417 (sezolamide) is a topically active carbonic anhydrase inhibitor. The effect of additional treatment with sezolamide 1.8% twice daily to patient already receiving timolol 0.5% twice daily was investigated. For this purpose, 12-h diurnal curves were used in a double-masked, randomized, placebo-controlled, parallel study in 36 patients with bilateral primary open angle glaucoma or ocular hypertension who during beta blocker therapy had intraocular pressures (IOP) greater than or equal to 22 mmHg. For 15 days patients received sezolamide or placebo 10 min after 0.5% timolol given at 8 a.m. and 8 p.m. On treatment day 15, this addition of sezolamide twice daily induced a further mean decrease in IOP of approximately 4 mm Hg (about 15%) at 1, 2 and 4 h and of approximately 2-3 mm Hg at 0, 6, 8, 10 and 12 h after drug administration, thus demonstrating a partial additive effect of sezolamide and timolol. Thus, sezolamide may be a useful addition to the treatment of glaucoma in patients not adequately controlled by beta blocker therapy.

Aged↗
PubMed1989

[Neuroborreliosis--not only Bannwarth's syndrome].

Two patients with neuroborreliosis are reported. They had Bannwarth's syndrome combined with encephalitis and myelitis respectively. Both patients recovered following high-dose penicillin treatment. Neuroborreliosis may be complicated with CNS involvement although this may be infrequent. It is important to diagnose neuroborreliosis because of the striking effect of penicillin treatment.

Aged↗
PubMed1989

Computerized tomography findings among workers with chronic intoxication of the brain.

Among the subjects classified as possibly or definitely demented 60% had suspected or definitely cerebral atrophy on CTs. Among the subjects classified as definitely demented 42% had definite cerebral atrophy. None of the referents had definite atrophy on CT. Regional cerebral blood flow was significantly decreased among subjects with cerebral atrophy. Some group overlap was evident as 12 subjects classified as definitely demented had normal CTs. This overlap showed that the absence of cerebral atrophy did not exclude the presence of dementia. On the other side, cerebral atrophy should not be found by a mere coincidence among persons under the age of sixty but indicates the presence of dementia.

Adult↗
PubMed1988

Cluster headache-like headaches: a symptomatic feature? A report of three patients with intracranial pathologic findings.

This report concerns three patients with cluster headache-like headaches associated with intracranial pathologic findings. The question whether the occurrence of cluster headache-like headaches may be a symptomatic feature is still not solved. In two of the three presented cases the cluster headache-like headaches disappeared when the intracranial abnormalities were treated.

Adenoma↗
PubMed1987

[Study on the incidence of Sarcocystis spp. in Dutch cattle using various methods].

Comparative studies were done to test the practicability of various methods of detection in bovine sarcosporidiosis. Macroscopic examination of meat, trichinoscopy and artificial digestion were carried out using meat from the heart and oesophagus. A total of ninety-one random animals were involved. It was concluded that artificial digestion of trypsin is the method of choice (practical, sensitive). As much as 100 per cent of the animals were found to be infected with Sarcocystis spp.

Animals↗
PubMed1985

Sarcosporidiosis--an overlooked zoonosis. Man as intermediate and final host.

Trichinoscopical investigation in 1971 revealed a prevalence rate of Sarcocystis infection of 2.8 percent in 49,000 sows and boars, and 0.67 percent in 60,000 bacon pigs. The investigation revealed ten percent infected stocks, showing that sarcosporidiosis is ubiquitous. Trichinoscopical examination of 112 specimens of human muscle tissue revealed four cases of sarcocystis infection corresponding to 3.6 percent-i.e., the rate of infection was comparable to that found in sows and boars. Man, when acting in the role of the final host, often exhibits severe symptoms of indigestion. Sarcocystis infection in the intermediate host may cause abortion. Could this happen in human cases as well? The fact that man acts as an intermediate as well as a final host indicates that sarcosporidiosis is a zoonosis.

Animals↗
PubMedDate not supplied

Isospora suis species in a Danish SPF-herd.

In two studies carried out in 1974-75 on 10 eight and 25 two week old piglets obtained from a SPF-herd the endoparasitic status was determined. Samples of faeces were examined by microscopy which revealed the presence of Isospora suis, a finding that was quite unexpected in a SPF-herd. During days 17-23 pp. the 25 piglets were not found to excrete oocysts, the earliest findings of oocysts being made 24-35 days p.p. The 10 piglets being kept isolated in individual pens excreted oocysts up until 88 days p.p. The epidemiology of Isospora suis is discussed.

Animals↗